A malignant transformation is known to occur in many nevi such as a sebaceous nevus or a basal cell nevus, but a verrucous epidermal nevus has only rarely been associated with neoplastic changes. Keratoacanthoma, multifocal papillary apocrine adenoma, multiple malignant eccrine poroma, basal cell carcinoma and cutaneous squamous cell carcinoma (CSCC) have all been reported to develop from a ver...

Inflammatory linear verrucous epidermal nevus is a rare variant of nevoid linear inflammatory dermatoses which appear most often in first six months of life and persists for many years or even whole life. Clinically it often shares many features with linear psoriasis, linear porokeratosis and other linear dermatoses which can usually be differentiated by an established set of clinical and histo...

Verrucous carcinoma (VC) is an exophytic, low-grade, well-differentiated variant of squamous cell carcinoma. It is described as a lesion appearing in the sixth or seventh decade of life that has minimal aggressive potential and, in long-standing cases, has been shown to transform into squamous cell carcinoma. Oral submucous fibrosis (OSMF) is a potentially malignant disorder, and about one-thir...

snus (nass) is a form of snuff used in a similar manner to american dipping tobacco, but it does not typically result in a need for spitting. possible hazards associated with this material include malignant and premalignant lesions in the oral cavity and gastrointestinal tract. the use of smokeless tobacco has increased in the middle east in recent decades, particularly among teenagers and youn...

Two patients with histologically proven verrucous carcinoma of the vulva are presented. One patient was treated by simple vulvectomy because of inoperable growth, and the other was successfully managed by radical vulvectomy.

BACKGROUND Hemangiomas, usually, present at the first few months of life and are the most common benign tumor in children. There are various therapeutic methods for hemangioma. Capillary hemangioma is a type of hemangiomas. The steps of treatment of a child with capillary hemangioma in Taleghani Hospital of Gorgan, Iran, are reported. CASE REPORT In this report, it is described an 18-month-ol...

sclerosing hemangioma of the lung is extremely rare.  herein, a case of sclerosing hemangioma of the lung in a 44-year-old woman is reported.  on admission, the patient complained of pain in the left lower neck and upper chest.  chest x-ray revealed a mass in lingular lobe of the left lung.  the patient underwent surgery and a mass was removed through left posterolateral thoracotomy.  pathologi...

Infantile hemangioma, a common benign tumor of infancy, grows quickly in the first year of life, and then regresses slowly to fibrofatty tissue in childhood. The accumulation of fibrofatty tissue in hemangioma involution indicates adipogenesis during this period. Perivascular cells (PCs) from multiple organs display multi-lineage differentiation, including adipogenesis. So we supposed that PCs ...

Infantile hemangioma (IH) is a common childhood vascular tumor. Although benign, some hemangiomas cause deformation and destruction of features or endanger life. The current treatments, corticosteroid or propranolol, are administered for several months and can have adverse effects on the infant. We designed a high-throughput screen to identify the Food and Drug Administration-approved drugs tha...