نتایج جستجو برای: ventral tegmental area

تعداد نتایج: 609305  

2002
Michael Tapper

Camera calibration is an important step in the initialisation of many stereo vision systems. The accuracy of camera parameters has a marked effect on the data obtained from a stereo vision system. In this paper, we describe some difficulties met in an attempt to build a calibration system based on Tsai’s Algorithm [Tsai, 1987]. We also offer some methods to overcome these problems. An overview ...

Journal: :Brain research 1999
D Yoganarasimha B L Meti

Intracranial self-stimulation (ICSS) rewarding experience is known to modulate learning and memory and induce morphological and neurochemical changes in hippocampus. Therefore, we studied the effect of ICSS on the hippocampus-dependent operant and the spatial learning tasks in rats with bilateral electrolytic lesioning of fornix. Bilateral lesioning of fornix induced deficits in acquisition and...

Journal: :PLoS ONE 2009
Natalia P. Bondar Ul'yana A. Boyarskikh Irina L. Kovalenko Maxim L. Filipenko Natalia N. Kudryavtseva

BACKGROUND It is generally recognized that recurrent aggression can be the result of various psychiatric disorders. The aim of our study was to analyze the mRNA levels, in the ventral tegmental area (VTA) of the midbrain, of the genes that may possibly be associated with aggression consistently shown by male mice in special experimental settings. METHODOLOGY/PRINCIPAL FINDINGS The genes were ...

2013
Hsiao-Lun Ku Chia-Shu Lin Hsiang-Tai Chao Pei-Chi Tu Cheng-Ta Li Chou-Ming Cheng Tung-Ping Su Ying-Chiao Lee Jen-Chuen Hsieh

Individuals with gender identity disorder (GID), who are commonly referred to as transsexuals (TXs), are afflicted by negative psychosocial stressors. Central to the psychological complex of TXs is the conviction of belonging to the opposite sex. Neuroanatomical and functional brain imaging studies have demonstrated that the GID is associated with brain alterations. In this study, we found that...

Journal: :Cold Spring Harbor perspectives in medicine 2013
Christian Lüscher

Cocaine leads to a strong euphoria, which is at the origin of its recreational use. Past the acute effects, the drug leaves traces in the brain that persist long after it has been cleared from the body. These traces eventually shape behavior such that drug use may become compulsive and addiction develops. Here we discuss cocaine-evoked synaptic plasticity of glutamatergic transmission onto dopa...

Firouz Ghaderi Pakdel, Mostafa Ashrafi Osalou, Parviz Shahabi, Sanaz Amirabadi, Somayyeh Naderi, Ulker Cankurt,

Introduction: The most common interpretation for the mechanisms of antidepression is the increase of the brain monoamine levels such as dopamine (DA). The increase of DA can reduce depression but it can also decrease the monoamine release because of autoreceptor inhibition. Although bupropion can decrease the dopamine release, there is evidence about stimulatory effects of chronic application o...

Aim 3,4-methylenedioxymethamphetamine (MDMA) is one of the most widespread illegal drugs, used particularly by young people in the 15-34 age group. MicroRNAs (miRNAs) are endogenously synthesized, non-coding and small RNAs that post-transcriptionally regulate their target genes’ expression by inhibiting protein translation or degradation. miRNAs are increasingly implicated in drug-related...

Journal: :Polish journal of pharmacology 2004
Wojciech Kostowski Andrzej Bidziński Paweł Krzaścik Janusz Szyndler Paulina Rok Paulina Kołomańska Aleksandra Wisłowska Małgorzata Lehner Adam Płaźnik

In the present study, we investigated the [(3)H]citalopram binding using a quantitative autoradiography following intracerebroventricular injection of 5,7-dihydroxytryptamine (5,7-DHT) in neonatal and adult male Wistar rats. One group of animals was injected with 5,7-DHT at 3 days after birth while the second group received the neurotoxin at 3 months after birth. Control group was injected with...

Journal: :Brain Research 2011
Patrícia S. do Nascimento Gisele A. Lovatel Sílvia Barbosa Jocemar Ilha Lígia A. Centenaro Tais Malysz Léder L. Xavier Beatriz D. Schaan Matilde Achaval

The aim of this study was to evaluate the effects of treadmill training on motor skills and immunoreactivity to tyrosine hydroxylase in the substantia nigra pars compacta and ventral tegmental area from diabetic rats induced by streptozotocin. Male Wistar rats were divided into three groups: control, diabetic and trained diabetic. Treadmill training was performed for 8weeks. Blood glucose conce...

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