BACKGROUND Syncope, the sudden transient loss of consciousness due to multiple etiologies, usually has worse outcomes in African Americans compared with other races because of other comorbidities. This study aims to identify a correlation between the etiologies of syncope and age in a predominantly African-American sample population to facilitate future investigations with potentially improved ...

BACKGROUND Natural history of Vasovagal syndrome (Neurocardiogenic; NCS) is unclear. AIM To examine symptoms in a large cohort with head up tilt diagnosed NCS. METHODS Questionnaires were posted to 485 patients with NCS. Data included demographic details, age at referral, presenting and on-going symptoms (syncope, dizziness and falls), symptom frequency (daily, weekly, monthly) and burden. ...

Abstract The cause of syncope remains unknown in about 40% of cases after extensive investigations. Elderly patients are at increased risk of syncope because of the physiologic changes due to aging, higher incidence of chronic illness and the use of a greater number of medications that may contribute to hypotension. Syncope is common, difficult to evaluate and has a high morbidity and mortality...

SEE PAGE 1 M any drugs have been tested for the treatment of vasovagal syncope; for the most part, the results have been disappointing. The list includes beta-blockers, disopyramide, scopolamine, theophylline, ephedrine, etilefrine, midodrine, clonidine, and serotonin reuptake inhibitors. Although results have been satisfactory in uncontrolled trials or short-term controlled trials, the few lon...

OBJECTIVE To evaluate the efficacy of head up tilt guided treatment with metoprolol and clonidine in preventing the recurrence of syncope in patients with malignant vasovagal syncope. PATIENTS 20 patients (9 men and 11 women, mean age 33 (SD 17), range 14 to 62 years) with severe symptoms. DESIGN Randomised double blind crossover trial; efficacy was assessed by head up tilt testing. RESUL...

The purpose of this study was to observe the hemodynamic changes of unexplained syncope patients in the head-up tilt test and their correlations with age and gender. Eighty-six patients with unexplained syncope were administered the basic head-up test and nitroglycerin provocation test with continuous monitoring and recording of electrocardiogram and blood pressure changes. Basic characteristic...

A 28-year-old female with a history of situational syncope and a new-onset right sided hemiparesis is described. Tilt-up table test revealed the postural orthostatic tachycardia syndrome followed by vasovagal syncope. Neurological and internal medicine tests showed no particular disorders. The patient underwent autonomic physical training and the tilt-up test performed three months later showed...

Pediatric syncope is a common problem that peaks in adolescence, for which there are few data or evidence-based consensus on investigation and management. This document offers guidance for practical evaluation/management of pediatric patients (age < 19 years) with syncope encountered in the acute or primary care setting. The writing committee used the Grading of Recommendations, Assessment, Dev...

Isolated syncope is a rare manifestation of seizures in children and it is a poorly localizing sign in the evaluation of seizures in children. Many times, such episodes are mistaken as primary cardiac dysrhythmias and we present herewith one such case in a child, who succumbed to the illness despite treatment.

Syncope is a common clinical presentation. Although most commonly benign, it may herald a pathology with a poor prognosis. The work-up of syncope includes a careful history, physical examination, electrocardiogram, risk stratification, and appropriately directed testing. The key factor in the investigation of syncope is the presence (or absence) of structural heart disease or an abnormal electr...