Noncoronary vasa vasorum have been described as networks of microvessels in the wall of arteries and veins. However, we have shown, using microcomputerized tomography (micro-CT) imaging methods, that porcine coronary vasa vasorum have a tree-like branching structure similar to the vasculature in general. In this study, we elucidate functional aspects of coronary vasa vasorum perfusion territori...

Cytoplasm at the posterior pole of the early Drosophila embryo, known as polar plasm, serves as a source of information necessary for germ cell determination and for specification of the abdominal region. Likely candidates for cytoplasmic elements important in one or both of these processes are polar granules, organelles concentrated in the cortical cytoplasm of the posterior pole. Females homo...

Vasa is a broadly conserved DEAD-box RNA helicase associated with germ line development and is expressed in multipotent cells in many animals. During embryonic development of the sea urchin Strongylocentrotus purpuratus, Vasa protein is enriched in the small micromeres despite a uniform distribution of vasa transcript. Here we show that the Vasa coding region is sufficient for its selective enr...

OBJECTIVE To examine the diagnostic precision of ultrasound examination for placenta accreta in women with placenta previa and to compare the morbidity associated with accreta to that of previa alone. METHODS This was a retrospective cohort study of all women with previa with/without accreta examined at the University of California, San Francisco (UCSF) between 2002 and 2008. The sensitivity,...

BACKGROUND The risk of placenta previa may be increased in pregnancies conceived by assisted reproduction technology (ART). Whether the increased risk is due to factors related to the reproductive technology, or associated with maternal factors, is not known. METHODS In a nationwide population-based study, we included 845,384 pregnancies reported to the Medical Birth Registry of Norway betwee...

The vasa gene encodes an ATP-dependent RNA helicase belonging to the DEAD-box family that, in many organisms, is specifically expressed in germline cells throughout the life cycle. In this study we first cloned Pacific white shrimp (Litopenaeus vannamei) partial cDNAs of two members of the DEAD-box family, one belonging to the vasa subfamily (Lv-Vasa) and the other to the PL10 subfamily (Lv-PL1...

BACKGROUND Placenta previa, a major cause of obstetric hemorrhage, is potentially life-threatening to the mother and frequently results in high perinatal morbidity and mortality. METHODOLOGY This is a retrospective study of all cases of placenta previa managed at the University of Ilorin Teaching Hospital over a 5-year from January 2011 to December 2015. A pro forma template was used to harve...

Vasa is essential for germline development. However, the precise processes in which vasa involves vary considerably in diverse animal phyla. Here we show that vasa is required for primordial germ cell (PGC) migration in the medakafish. vasa knockdown by two morpholinos led to the PGC migration defect that was rescued by coinjection of vasa RNA. Interestingly, vasa knockdown did not alter the PG...

Dangerous placenta previa refers to somebody has a history of cesarean section while this pregnancy was placenta previa with the placenta attached to the original scar. The placenta can be adhered to the surface of the uterus, invasion into myometrium or completely penetrate the muscle and tissues in these placenta previa patients. It happens in these persons like older maternal ages (over 35 y...