نتایج جستجو برای: variation complex
تعداد نتایج: 1059148 فیلتر نتایج به سال:
For QTL mapping of related salt tolerance QTLs and determining the contribution of each QTL to phenotypic variation, a population consisting of 96 F2:3 families derived from the cross Kharchia (parent tolerant) and Gaspard (susceptible parent) were evaluated during 2 years. Of the 92 microsatellite markers used to evaluate parents, 32 markers were polymorphic which were used for analysis. Three...
Background: Malaria is still one of the main health problems in south and southeast provinces of Iran and recently on average 10,000-30,000 malaria cases were reported annually. Mosquitoes of Anopheles superpictus are one of the main malaria vectors in Iran and have been reported from all areas of the country including central plateau and plains of Alborz and Zagrous Mountains chains, and with ...
Copy number variants (CNVs) play an important role in human disease and population diversity. Advancements in technology have allowed for the analysis of CNVs in thousands of individuals with disease in addition to thousands of controls. These studies have identified rare CNVs associated with neuropsychiatric diseases such as autism, schizophrenia, and intellectual disability. In addition, copy...
Genome structural variation (SV) is a major source of genetic diversity in mammals and a hallmark of cancer. Although SV is typically defined by its canonical forms (duplication, deletion, insertion, inversion and translocation), recent breakpoint mapping studies have revealed a surprising number of 'complex' variants that evade simple classification. Complex SVs are defined by clustered breakp...
Loss or gain of DNA methylation can affect gene expression and is sometimes transmitted across generations. Such epigenetic alterations are thus a possible source of heritable phenotypic variation in the absence of DNA sequence change. However, attempts to assess the prevalence of stable epigenetic variation in natural and experimental populations and to quantify its impact on complex traits ha...
Hundreds of copy number variants are complex and multi-allelic, in that they have many structural alleles and have rearranged multiple times in the ancestors who contributed chromosomes to current humans. Not only are the relationships of these multi-allelic CNVs (mCNVs) to phenotypes generally unknown, but many mCNVs have not yet been described at the basic levels-alleles, allele frequencies, ...
Random amplified polymorphic DNA markers (RAPD) were used ro delimit species in the tj}(1cris tas/J1rmica complex (Epacridaceae) collected from various locations in Tasmania, Australia. The RAPD analysis placed morphologically similar taxa located closely geographically into discrete dusters. However, geographically distant populations of morphometrically similar taxa, such as rhe southern and ...
Association studies provide genome-wide information about the genetic basis of complex disease, but medical research has focused primarily on protein-coding variants, owing to the difficulty of interpreting noncoding mutations. This picture has changed with advances in the systematic annotation of functional noncoding elements. Evolutionary conservation, functional genomics, chromatin state, se...
The major histocompatibility complex (MHC) is a fundamental part of the vertebrate immune system, and the high variability in many MHC genes is thought to play an essential role in recognition of parasites. The Przewalski's horse is extinct in the wild and all the living individuals descend from 13 founders, most of whom were captured around the turn of the century. One of the primary genetic c...
— We show that the limit, by rescaling, of the ‘new supersymmetric index’ attached to the Fourier-Laplace transform of a polarized variation of Hodge structure on a punctured affine line is equal to the spectral polynomial attached to the same object. We also extend the definition by Deligne of a Hodge filtration on the de Rham cohomology of a exponentially twisted polarized variation of comple...
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