Telomerase and systems controlling their activity have been of great attention. There are controversies regarding the role of the alternative splicing forms of the human telomerase reverse transcriptase (hTERT), the catalytic subunit of telomerase. Therefore, the correlation between telomerase enzyme activity, the abundance of alternatively spliced variants of hTERT and doubling time of a seri...

Introduction: Pathogenic variants of RUNX2, a gene that encodes an osteoblast-specific transcription factor, have been shown as the cause of CCD, which is a rare hereditary skeletal and dental disorder with dominant mode of inheritance and a broad range of clinical variability. Due to the relative lack of clinical complications resulting in CCD, the medical diagnosis of this disorder is challen...

leiomyomas are benign tumors of the soft tissue and may develop in any location where smooth muscle is present. leiomyoma in the inferior vena cava is a rarely seen pathology, and symplastic leiomyoma is also a rare histological variant of leiomyoma. in this case, we present a rare histological variant of symplastic leiomyoma in the inferior vena cava (ivc). this is the first radiologically rep...

We consider two-dimensional turbulence driven by a steady prescribed sinusoidal body force working at an average rate epsilon. Energy dissipation is due mainly to drag, which damps all wave number at a rate micro. Simulations at statistical equilibrium reveal a scaling regime in which epsilon proportional, variant micro;{1/3}, with no significant dependence of epsilon on hyperviscosity, domain ...

Helicopter landing sites in proximity to the forest fire-risk zones are necessary for the delivery of supplies and fire emergency response teams. In this paper, we initially prepared forest fire risk map using Random Forest algorithm by overlaying the effective factors on fire occurring including vegetation types, physiographic, climatic and human factors. Then, three variants of natural candid...


 a variant of fixed point theorem is proved in the setting of s-metric spaces

abstract background and aim: survivin is a new member of inhibitor of apoptosis protein family (iap) that plays an important role in the regulation of cell cycle and inhibition of apoptosis. distinct expression of this gene in tumoral cells versus normal cells introduces it as the fourth major transcriptome in cancers. thyroid carcinoma is the most common endocrine malignancy. considering the h...

hereditary ataxias are heterogeneous group of neurodegenerative disorders classified mainly into more than 40 autosomal dominant cerebellar ataxias and 50 recessive ataxias. large amount of nearly uncommon subtypes with extensive phenotypic overlap and relatively high rate of abnormal repetitive sequence expansions, such as trinucleotide repeat expansions make diagnostic genetic testing complic...

We developed a new semi-supervised EM-like algorithm that is given the set of objects present in eachtraining image, but does not know which regions correspond to which objects. We have tested thealgorithm on a dataset of 860 hand-labeled color images using only color and texture features, and theresults show that our EM variant is able to break the symmetry in the initial solution. We compared...