The aim of this study was to evaluate the effectiveness of low molecular weight hyaluronic acid oral tablets for the treatment of atrophic vaginitis. 12 women with atrophic vaginitis were recruited for this double blind, placebo-controlled study. Patients were randomized to receive either low molecular weight hyaluronic acid (HA) oral tablets or placebo for three months. Vaginal biopsies were t...

To the Editor: We have read with great interest the recently published article by Gerber et al. (1) on the potential endometrial benefit of anastrozole given to postmenopausal breast cancer patients with tamoxifen-induced endometrial pathology. Their study showed that the switch to anastrozole significantly reduced the need for a second invasive gynecologic procedure for recurrent vaginal bleed...

Methods This is a prospective, double blind study. Fifty female patients, 20 to 50 (mean 35) years old, were evaluated in two study groups: group1 – 30 patients with vaginal delivery and episiotomy and group2 – 20 patients with caesarean operation and without episiotomy (control for episiotomy). The patient selection was done clinically. Pelvic magnetic resonance (1.5T) examinations with turbo ...

Treatment with aromatase inhibitors for postmenopausal women with breast cancer has been shown to reduce or obviate invasive procedures such as hysteroscopy or curettage associated with tamoxifen-induced endometrial abnormalities. The side effect of upfront aromatase inhibitors, diminished estrogen synthesis, is similar to that seen with the natural events of aging. The consequences often inclu...

Hormonal vaginal therapy is an effective treatment option for women who experience symptoms related to hormonal changes. Estrogen and prasterone are widely used as treatments, particularly urogenital atrophy. These may include dryness, itching, burning, pain during sexual intercourse, all of which can significantly affect a woman’s quality life. Previous studies have indicated that such improve...

objective a 4-month-old female with osteogenesis imperfecta (oi) type ii was admitted in picu of our center due to severe respiratory distress and fever with a diagnosis of severe pneumonia, and mechanical ventilation was initiated. due to severe hypotonia, ncv and emg were performed, and spinal muscular atrophy (sma) type i was diagnosed.

OBJECTIVE This pilot study aimed to assess the efficacy and feasibility of fractional CO2 laser in the treatment of vulvovaginal atrophy (VVA) in postmenopausal women. METHODS VVA symptoms were assessed before and after three applications of laser over 12 weeks in 50 women (age 59.6 ± 5.8 years) dissatisfied with previous local estrogen therapies. Subjective (visual analog scale) and objectiv...