Prohibitin (PHB) plays a role in regulation of ultraviolet B light (UVB)-induced apoptosis of human keratinocytes, HaCaT cells. The regulatory function of PHB appears to be associated with its lipid raft translocation. However, the detailed mechanism for PHB-mediated apoptosis of these keratinocytes upon UVB irradiation is not clear. In this report, we determined the role of lipid raft transloc...

Ultraviolet B (UVB) triggers lupus flare by worsening skin lesions and systemic symptoms, i.e. nephritis. We have reported that UVB exposure induces inflammation with neutrophil infiltration extracellular trap (NET) formation in mice. also found induced proteinuria young female lupus-prone The relevant mechanisms regarding dermal-renal crosstalk is unclear. examined lesions, proteinuria, of neu...

BACKGROUND Lasers and light sources emitting ultraviolet B (UVB) irradiation have been shown to repigment striae distensae. OBJECTIVE The purpose of this study was to analyze the histologic and ultrastuctural changes seen after UVB laser- or light source-induced repigmentation of striae distensae. METHODS Ten subjects with hypopigmented striae were selected. Five subjects were treated with ...

BACKGROUND Atopic dermatitis (AD) is a genetically determined pruritic skin disease affecting predominantly young people. The therapy of AD includes mainly corticosteroids (CS), antihistamines and immunosuppressors. CS are known to cause a variety of side effects and attempts have been made to reduce or eliminate their use through alternative methods such as phototherapy (UVA/UVB, UVA(1), UVB 3...

Theabrownin is a heterogeneous polyphenolic compound, obtained from fermented dark teas, with many bioactive functions. However, the role of theabrownin in skin photoaging remains unclear. In this study, we investigated whether modulates ultraviolet B (UVB)-induced matrix metalloprotease-1 (MMP-1) expression HaCaT keratinocytes. exerted antioxidant properties, which resulted scavenging intracel...

Subpopulations of primary nociceptors (C- and Aδ-fibers), express the TRPV1 receptor for heat capsaicin. During cutaneous inflammation, these afferents may become sensitized, leading to hyperalgesia. It is known that TRPV1+ are involved in hyperalgesia; however, their involvement mechanical hyperalgesia unclear. This study explored contribution capsaicin-sensitive development humans following u...

To combat vitamin D insufficiency in a population, reliable diet sources of vitamin D are required. The recommendations to consume more oily fish and the use of UVB-treated yeast are already applied strategies to address vitamin D insufficiency. This study aimed to elucidate the suitability of plant oils as an alternative vitamin D source. Therefore, plant oils that are commonly used in human n...

Psoralen plus ultraviolet A (PUVA) is widely used as first-line therapy for treatment of mycosis fungoides. Narrowband ultraviolet B (NB-UVB) has also been shown to be effective for treatment of early mycosis fungoides. The aim of this retrospective study was to analyse the response to treatment and relapse-free interval for PUVA and NB-UVB therapies in mycosis fungoides. Forty patients were tr...