BACKGROUND Skin lesions in pregnant women could be caused by physiologic or pathologic changes. Polymorphic eruption of pregnancy (PEP), which manifests as various types of skin lesions, is the most common pregnancy dermatosis. Thus, PEP could mimic other skin diseases related to unfavorable maternal and fetal outcomes. MAIN OBSERVATIONS Two PEP patients with targetoid lesions are presented h...

Abstract An 81‐year‐old Japanese man presented with a history of recurrent eyelid swelling and purpura on the face, neck, limbs. Because initial clinical presentation was angioedema alone, patient treated an H1‐receptor antagonist tranexamic acid as for idiopathic angioedema. The also experienced dyspnea simultaneously edema face limbs thus taken to emergency room, where laryngeal confirmed fib...

COVID-19 is a global pandemic caused by novel zoonotic RNA virus named SARS-CoV-2. Various cutaneous manifestations associated with have been described, including urticarial rash, confluent erythematous papulovesicular exanthem, chilblain-like acral pattern, livedo reticularis, and purpuric vasculitis pattern. Here, we are presenting case of 45-year-old male mucocutaneous features Stevens-Johns...

Introduction: We report a patient with history of red meat allergy, or alpha-gal syndrome, who had an urticarial rash after exposure to unfractionated heparin at dose typically used for prophylaxis deep venous thrombosis. Although anaphylactic reactions have been reported systemic intravenous heparin, we believe this case is the first immunoglobulin E–mediated reaction subcutaneous prophylactic...