نتایج جستجو برای: urothelial carcinoma in situ
تعداد نتایج: 17047993 فیلتر نتایج به سال:
cytomorphological changes of mitomycin c on urothelial cells may be misinterpreted as a neoplastic process. a 60-year old male patient who was given an eight-week course of intravesical mitomycin c due to non-invasive low grade transitional cell carcinoma. during his follow-up care, the findings of a urine cytology exam were as follows: nuclear enlargement of cells, wrinkled nuclear membranes, ...
Bladder cancer has the highest recurrence rate of any solid tumor. Due to the need for lifelong surveillance, the per-patient cost of managing bladder cancer is among the highest for any cancer. There has been growing activity in the development of novel markers for bladder cancer detection; the ultimate goal of these novel markers would be to replace and/or complement cystoscopy as a sensitive...
OBJECTIVE To evaluate the value of liquid-based cytology (LBC) in the diagnosis of urothelial carcinoma. METHOD Diagnostic studies were searched for the diagnostic value of LBC in urothelial carcinoma in PubMed, Embase, Cochrane Library, Web of Science, CBM and CNKI. The latest retrieval date was September 2014. The data were extracted and the quality of the included studies was independently...
Object: To identify associations between 17β-hydroxysteroid dehydrogenase type 2 (HSD17B2) expression and clinicopathological variables and prognoses in patients with urothelial carcinoma of the urinary tract. Materials and Methods: We analyzed one public transcriptome dataset (GSE31684) from the Gene Expression Omnibus. HSD17B2 showed the highest log2-transformed fold-change in expression, and...
BACKGROUND To examine histopathologic features and clinical outcomes of intradiverticular bladder carcinomas. METHODS Twenty-two consecutive patients with intradiverticular bladder carcinoma treated with either endoscopic transurethral resection or partial or radical cystectomy at a single institution between years of 1995 to 2011. Clinicopathologic characteristics and oncologic outcomes of p...
AIMS To report on the clinicopathological features of 20 cases of microcystic urothelial bladder carcinoma. METHODS AND RESULTS The extent of microcystic component varied from 50-100% of the specimens. The cysts were round-oval and of varying sizes; the periphery of large cysts was frequently punctuated by many smaller cysts. The cysts were lined by urothelial, low columnar cells or by a sing...
BACKGROUND Pathological diagnosis of urothelial carcinoma (UC) is primarily based on cytological atypia. It has previously been shown that high-grade (HG) UC, particularly UC in situ cells (CIS), can be over five times the size of a lymphocyte. However, this has not been demonstrated in comparison to reactive urothelium. The objective of this study was to empirically compare the difference in n...
Objectives. The aim was to compare demographics and pathological features of bladder carcinoma treated in a urology unit with findings of previous studies done in Sri Lanka. Materials and Methods. Data of newly diagnosed patients with bladder cancer in a tertiary referral centre from 2011 to 2014 were analysed. Data on bladder cancers diagnosed from 1993 to 2014 were obtained from previous publ...
We analyzed a cohort of 599 cases of urothelial carcinoma for EGFR, ERBB2, and ERBB3 gene expression and genomic alterations. The cohort consisted of a reference set (n = 292) comprising all stages and grades and one set (n = 307) of advanced tumors. All cases were previously classified into urothelial carcinoma molecular subtypes. Genomic amplifications were established by array-CGH or in-situ...
Purpose: Metastatic urothelial carcinoma of the bladder is associated with multiple somatic copynumber alterations (SCNAs). We evaluated SCNAs to identify predictors of poor survival in patients with metastatic urothelial carcinoma treated with platinum-based chemotherapy. Experimental Design: We obtained overall survival (OS) and array DNA copy-number data from patients withmetastatic urotheli...
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