Many inborn errors of metabolism are characterized by an increase in the concentrations of various carboxylic acids in blood and urine. For example, the metabolic disorders propionic acidemia [ 11, methylmalonic aciduria [ 2,3], maple syrup urine disease [4], isovaleric acidemia [ 41 and glutaric aciduria type II [ 5,6] show increased amounts of volatile carboxylic acids in blood or urine. Proc...

A total of 384 pigs was used to evaluate the effects of benzoic acid supplementation on nitrogen balance of pigs compared to antibiotics and organic acids. Pigs were weaned at 21 d of age and fed 7 diets for 5 wk based on 3 phase feeding program following nutrient requirements from NRC. There were 8 replicates per treatment and 8 pigs per pen. Treatments were NC: negative control without any su...

most plants are able to increase soil phosphorus availability by exuding some compounds such as organic acids when they experience phosphorous deficiency. considering this special ability of plants, the main purpose of the present research was to investigate if application of organic acids may increase p availability in soil. therefore, a greenhouse experiment was conducted with five treatments...

glutaric acidemia, type i (ga i), was first described in 1975. the disease is caused by a genetic deficiency of the enzyme, glutaryl-coa dehydrogenase (gcd), which leads to the buildup of glutaric acid in the tissues and its excretion in the urine of affected patients. gcd is involved in the catabolism of the amino acids, lysine, hydroxylysine, and tryptophan. over 200 cases of ga i have been r...

BACKGROUND Patients with propionic acidemia usually present in the neonatal period with life-threatening ketoacidosis, often complicated by hyperammonemia. It was thought that the neurologic abnormalities seen in this disease were exclusively the consequences of these acute crises. Experience with 2 patients with propionic acidemia indicates that this disease may present first with prominent ne...

The chromatographic behavior of several simple phenolic acids was described recently, and a description of the phenolic acids present in human urine has been given (2). Experiments aimed towards establishing a preliminary identification of many of the urinary acids revealed that several compounds having the characteristics of m-hydroxyphenyl acids are found. These include m-hydroxyhippuric, -be...

Phytotoxicity of aluminium is one of the most serious problems in limiting plant growth in acidic soils. A number of plant species exhibit inheritable aluminium tolerance by the secretion of organic acids which is highly specific to aluminium stress and localized to the root apices. Organic acids have been considered to play an important role in the detoxification of aluminium, both externally ...

We describe the general aspects of ion chromatography and how on-line counted ion-exchange techniques can be utilized to determine pyruvic and lactic acids in plasma and vanillymandelic acid in urine. Pyruvate and lactate are extracted from deproteinized plasma by use of an ion-exclusion resin. After elution from the resin, the plasma extract is chromatographed on an anion-exchange column, with...

Experiments on hydrothermal degradation of Pyrococcus abyssi biomass were conducted at elevated pressure (40 MPa) over a 200-450 °C temperature range in sapphire reaction cells. Few organic compounds could be detected in the 200 °C experiment. This lack was attributed to an incomplete degradation of P. abyssi cells. On the contrary, a wide range of soluble organic molecules were generated at te...

Anaerobic digestion is the breakdown of biodegradable organic material by microorganisms in the absence of oxygen or in an oxygen-starved environment.This technology is superior to the landfilling and also the aerobic composting. The aim of the present study was to examine whether the effluent Volatile Fatty Acids from the anaerobic acidogenesis of the food waste can be used du to its high valu...