A decrease in load-bearing activity, as experienced during spaceflight or immobilization, affects the musculoskeletal system in animals and humans, resulting in the loss of bone and connective tissue. It has been suggested that hypergravity (HG) can counteract the deleterious effects of microgravity-induced musculoskeletal resorption. However, little consensus information has been collected on ...

In northern Tanzania large numbers of small scale miners use mercury in the gold extraction process causing contamination of the environment and risks to human health. Human exposure to Hg was assessed in populations in and around small scale gold mining camps by means of human hair and urine surveys. We also determined Hg concentration in fish in aquatic bodies close to these camps. Urinary Hg...

STUDY OBJECTIVES We studied the effect of continuous positive airway pressure (CPAP) treatment on sympathetic nervous activity in 38 patients with obstructive sleep apnea. DESIGN Randomized, placebo-controlled trial. SETTING Patients underwent polysomnography on three occasions in a clinical research center, and had BP monitored over 24 h at home. All of the patients had sleep apnea with a ...

Methylmercury (MeHg) exposure during pregnancy is a concern because of its potential health risks to the fetus. Wheat bran (bran), which outer layer wheat kernel, used as functional substance in food for specified uses Japan. In present study, we examined effect on accumulation and excretion Hg mice evaluate use reducing risk MeHg. Female BALB/cByJ were administered MeHg chloride (4 mg Hg/kg, p...

The renal handling of phosphorus was evaluated in rats with acute renal failure (ARF) induced by injection of mercuric chloride (HgCl(2)). Clearances of endogenous creatinine (Ccr) and of phosphorus (Cp) were measured in the following groups: 1. Intact animals (control); 2. Parathyroidectomized rats (PTX) with normal kidney function (PTX control); 3. Animals with mercury-induced acute renal fai...

The ability of selenium (Se) to moderate mercury (Hg) toxicity is well established in the literature. Mercury exposures that might otherwise produce toxic effects are counteracted by Se, particularly when Se:Hg molar ratios approach or exceed 1. We analyzed whole body Se and Hg concentrations in 468 fish representing 40 species from 137 sites across 12 western U.S. states. The fish samples were...

BACKGROUND Diabetic nephropathy is the major cause for chronic renal failure (CRF) and proteinuria is an independent risk factor for end stage renal disease. Hence, early identification and quantification of proteinuria is of prime importance in the diagnosis and management. METHODS This study was conducted amongst 42 diabetic subjects from HSK hospital, Bagalkot. Twenty four-hour urine prote...

Hyperemesis gravidarum (HG) occurs in 0.3% to 2% of all pregnancies and was found to be the second most common indication for admission in pregnant women who later gave birth to a live infant [1]. The present study aimed to determine the ability of the main laboratory indicators of hyperemesis gravidarum severity to predict hospital stay at first hospitalization. Records taken in 2004 of the fi...

We report a gas-chromatographic method for the simultaneous quantitative analysis of both glutethimide and 4-hydroxy-2-ethyl-2-phenylglutarimide (4HG), an active metabolite of glutethimide, in tissues, plasma, and urine. The method, applied to postmortem tissues from cases of fatal glutethimide overdose and to plasma samples obtained from a patient in coma from acute glutethimide intoxication, ...