upregulation

Toni Jernfors Jenni Kesäniemi Anton Lavrinienko Tapio Mappes Gennadi Milinevsky Anders P. Møller Timothy A. Mousseau Eugene Tukalenko Phillip C. Watts

Citation: Jernfors T, Kesäniemi J, Lavrinienko A, Mappes T, Milinevsky G, Møller AP, Mousseau TA, Tukalenko E and Watts PC (2018) Transcriptional Upregulation of DNA Damage Response Genes in Bank Voles (Myodes glareolus) Inhabiting the Chernobyl Exclusion Zone. Front. Environ. Sci. 5:95. doi: 10.3389/fenvs.2017.00095 Transcriptional Upregulation of DNA Damage Response Genes in Bank Voles (Myode...

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Inhibition of mitogen-activated protein kinase pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment

2014

Kousaku Mimura Ley-Fang Kua Kensuke Shiraishi Lim Kee Siang Asim Shabbir Mayumi Komachi Yoshiyuki Suzuki Takashi Nakano Wei-Peng Yong Jimmy So Koji Kono

Recently, we reported that human leukocyte antigen (HLA) class I expression is predominantly regulated by the mitogen-activated protein kinase (MAPK) pathway as one of the oncogenic regulations of HLA class I expression. In the present study, we examined mechanisms of how HLA class I and PD-L1 are regulated by MAPK inhibitors and interferon-γ (IFN-γ). Furthermore, we evaluated the expression of...

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