Sonic hedgehog promotes proliferation of developing cerebellar granule cells. As sonic hedgehog is expressed in the cerebellum throughout life it is not clear why proliferation occurs only in the early postnatal period and only in the external granule cell layer. We asked whether heparan sulfate proteoglycans might regulate sonic hedgehog-induced proliferation and thereby contribute to the spec...

in this paper, we establish some new results in ultra bessel sequences and ultra bessel sequences of subspaces. also, we investigate ultra bessel sequences in direct sums of hilbert spaces.specially, we show that {( fi, gi)}∞ i=1 is a an ultra bessel sequencefor hilbert space h ⊕ k if and only if { fi}∞ i=1 and {gi}∞ i=1 are ultrabessel sequences for hilbert spaces h and k, respectively.

This paper develops the idea of ‘instrumentality’ to explore how use diverse tools or instruments involved in new music have potential (re)frame our engagement with world. It will be argued that choice instrumental and they are used performance can not only enrich creative processes outcomes for artist but also alter audience’s relationship world by encouraging a conceptual one more its aspects...

Every day, the technologies are expanding and developed with extra things to them. A cloud computing (CC) Internet of (IoT) became deeply associated internet future one supply other a way helping it for successful. Arduino microcontroller is used design robotic arm pick place objects by web page commands that can be in many industrials. It an object from source destination drive screws into its...

Background. This in vitro study aimed to compare the antibacterial effect of different concentrations of sodium hypochlorite on elimination of Enterococcus faecalis from root canal systems of primary teeth with or without a passive sonic irrigation system (EndoActivator). Methods. The root canals of 120 extracted single-rooted primary incisors were prepared using the crown-down technique. The t...

BACKGROUND Intestinal epithelial cells express the Sonic and Indian hedgehog ligands. Despite the strong interest in gut hedgehog signaling in GI diseases, no studies have specifically addressed the singular role of intestinal epithelial cell Sonic hedgehog signaling. The aim of this study was to investigate the specific role of Sonic hedgehog in adult ileal epithelial homeostasis. METHODOLOG...

Chinese is a tonal language. How lexical tones and intonation interplay with each other is an interesting question. In this study, we investigated emotional intonations by analyzing monosyllabic utterances from two speakers. We found that the tonal space, the edge tone and the duration differ greatly across 7 emotions, and that different speakers showed consistent production patterns. The speak...

Differentiation therapy is a means to treat cancer and is induced by different agents with low toxicity and more specificity than traditional ones. Diosgenin, a plant steroid, is able to induce megakaryocytic differentiation or apoptosis in human HEL erythroleukemia cells in a dose-dependent manner. However, the exact mechanism by which diosgenin induces megakaryocytic differentiation has not b...

BACKGROUND The loss of sonic hedgehog is an early change that occurs in the mucosa prior to neoplastic transformation and correlates with the type of intestinal metaplasia. Aberrant expression of CDX has also been shown to correlate with the development of intestinal metaplasia. AIM To examine CDX2 expression in the non-cancerous mucosa of patients with gastric cancer and compared it to CDX2 ...

The combination of psychophysiological and psychometric methods provides reliablemeasurements of affective user experience (UX). Understanding the nature of affective UX ininteractive entertainment, especially with a focus on sonic stimuli, is an ongoing researchchallenge. In the empirical study reported here, participants played a fast-paced, immersive first-person shooter (FPS...