Crocin is a plant-derived carotenoid and bears potent antioxidant property. Ranitidine (a histamine H2 receptor blocker) is used for peptic ulcer treatment. The present study was planned to investigate the effects of crocin and ranitidine on indomethacin-induced ulcer in small intestine of rats. Animals were randomized into two major groups including indo-methacin (10.00 mg kg-1...

Objectives: To Evaluate Preliminary Pharmacological screening of plant extract Ficus Auriculata Lour for Anti - Ulcer activity.
 Materials and Methods: The fresh leaves ficus auriculata lour werecollected from the wild forest area village Mushyoli Distt. Bageshwar (Uttarakhand), India. identification authentication leaf’s ficusauriculta (BSI/NRC/Tech./Herb.(Ident.)/2019-20/433) was done by...

OBJECTIVE To investigate the threshold of transcutaneous oxygen tension (TcPO(2)) values in predicting ulcer healing in patients with critical limb ischaemia in a prospective study. METHOD 50 patients suffering from critical limb ischaemia with chronic ischemic ulcers or gangrenous toes were enrolled in this study between January and December 2008. Their demographic data and ankle brachial pr...

Introduction: Diabetes mellitus (DM) remains the major global health problem, predicted to exceed half a billion people in 2040. One of complications was lower extremity neuropathy leading foot ulcer and amputation. This study aimed investigate effect routine Buerger exercise on index with DM. Methods: A pre-and posttest quasi-experimental between May August 2018 involving DM patients primary c...

Gastric ulcers are a common gastrointestinal disease with complex etiology. It manifests various signs and symptoms, which, in severe cases, could be life-threatening, especially developing countries. Medicinal plants have been known to exhibit therapeutic potential minimal adverse effects thus employed treating diseases. This study evaluated the effect of ethanolic Myrianthus arboreus leaf ext...

BACKGROUND While the adverse impact of a history of a foot ulcer on physical health among persons with diabetes is well known, little is known about the association between foot ulcer, perceived health and psychological distress. Results from various studies are difficult to compare as different study designs, samples and/or different questionnaires have been used. The aim of this study was to ...

Pongamia pinnata has long been used in folk medicine in treatment for bronchitis, whooping cough, rheumatic arthritis, and diabetes, various inflammatory conditions and dyspepsia. Therefore, Present study was designed to investigate the antiulcer effect of hydroalcoholic extract of leaves of P. pinnata (HLEPP) using different models of gastric ulceration in rats. Hydroalcoholic extract of leave...

Aims: The present research is focused on screening in vivo anti-ulcer activity using pylorus ligation and ethanol induced ulcer model. 
 Study Design: Fourty eight rats, randomly divided into groups, were used this study. Bark of Alstonia scholaris air-dried, ground fine powder the preparation an ethanolic extract.
 Place Duration Study: Department Pharmacology, Osmania University, Hy...

OBJECTIVE To estimate the incidence and identify risk factors for lower-extremity pressure ulcers in bedfast older adult patients. DESIGN Prospective cohort study. SETTING A 500-bed long-term-care facility in Japan. PATIENTS A total of 259 patients who were aged 65 years or older, confined to bed, and without lower-extremity pressure ulcers at enrollment participated in the study. MAIN ...