Helicobacter pylori infection is endemic in Korea, and serology testing is widely performed. The aim of this study was to validate and compare the diagnostic accuracy of Korean and Western serological assays for H. pylori detection in Korean adults. The 114 Korean adults who visited our centre over a 6-month period for the evaluation of H. pylori infection using the urea breath test (UBT) were ...

BACKGROUND & AIMS We investigated whether serum levels of pepsinogen (sPG)I and sPGII, the ratio of sPGI to sPGII, or serum levels of gastrin-17 (sG17), can be used to assess eradication of Helicobacter Pylori 8 weeks after treatment. METHODS We performed a prospective study of 228 consecutive patients with H pylori infections. At the start of the trial (baseline), patients were assessed usin...

Among the methods developed to detect H. pylori infection, determining the gold standard remains debatable, especially for epidemiological studies. Due to the decreasing sensitivity of direct diagnostic tests (histopathology and/or immunohistochemistry [IHC], rapid urease test [RUT], and culture), several indirect tests, including antibody-based tests (serology and urine test), urea breath test...

INTRODUCTION Recent studies found that Helicobacter pylori (H. pylori) infection plays a role in cardiometabolic disorders. The objective of this study was to assess the association between H. pylori infection and overweight or obesity in a Chinese population. METHODOLOGY A cross-sectional analysis using data from the subjects who underwent a health examination between January 2010 and June 2...

OBJECTIVES To determine the effect of Helicobacter pylori (H. pylori) eradication on blood levels of high-sensitivity C-reactive protein (hs-CRP), macrophage migration inhibitory factor and fetuin-A in patients with dyspepsia who are concurrently infected with H. pylori. METHODS H.pylori infection was diagnosed based on the 14C urea breath test (UBT) and histology. Lansoprazole 30 mg twice da...

In a recent interesting letter, Varas-Lorenzo and MuñozAgel reported on the prevalence of active Helicobacter pylori (Hp) infection in patients with inflammatory bowel disease (IBD). The authors demonstrated that the infection, diagnosed by 13C urea breath test (UBT), was present in 50% of patients with Crohn’s disease (CD), in 37% of patients with ulcerative colitis (UC) and in 40% of controls...

I read with interest the recent article by Sunnerstam et al. regarding their evaluation of available serologic tests for immunoglobulin G (IgG) antibodies to Helicobacter pylori in children (9). I agree that serologic methods used to determine H. pylori antibody status in children must be validated. It is well known that the performance of commercial assays designed to detect IgG antibodies to ...

background helicobacter pylori eradication with clarithromycin is more expensive than with azithromycin. objectives this study aimed to compare the effectiveness of these two antibiotics in eradicating h. pylori in hemodialysis (hd) patients. patients and methods this is a prospective, randomized, double-blinded clinical trial analysis of hd patients. patients who had dyspepsia and showed posit...