t cells have been identified as key players in the pathogenesis of type 1 diabetes. however, the exact role of t-cell subpopulations in this pathway is presently unknown. the purpose of this study was to assess the expression pattern of two lineage-specifying transcription factors gata - 3 and t - bet , which are important in t helper type 1 (th1) and th2 cell development , respectively. gene e...

objective: the aim of the present study was to investigate the prevalence of hypertension and type ii diabetes in elderly iranianresidents of the kahrizak charity foundation(kcf). materials and methods: in this cross-sectional study, a total of two hundred sixty eight men and women ≥60 years were studied. the data were collected during annual health examination of the elderly residents in kcf. ...

background: angiotensin i converting enzyme (ace) is a zinc metalloproteinase, converts ang-i to ang- ii, a pro-inflammatory agent which may contribute to pathophysiology of some diseases like type 2 diabetes. objective: to investigate the relationship between ace i/d polymorphism and type 2 diabetes in 261 iranian casecontrol pairs. methods: 170 patients (85 type 2 diabetics with nephropathy a...

background: diabetic nephropathy is considered to be the most common cause of end stage renal disease (esrd). proteinuria is declared as the most marked risk factor in progression towards esrd. the aim of this study was to evaluate the efficacy of pentoxifylline for reduction of proteinuria in type ii diabetic patients. methods: from may 2007 to june 2008, this randomized clinical trial study w...

background: diabetes is a major risk factor of chronic diseases such as cardiovascular disease with high mortality. prevalence of diabetes type 2 is increasing in middle eastand iran. in the current study, relationship between major food patterns and diabetes type 2 were assessed. methods: in this case control study, 332 subjects (110 newly diagnosed cases and 222 controls); 43-77 years of age ...

conclusions parental functioning and wellbeing are important aspects of a family adaptation to chronic pediatric conditions. moreover, psychological interventions were recommended to patients. results the abbreviation (gsi) score in leukemic children’s mothers was higher than t1dm children’s mothers and both groups had higher gsi compared with the control group. background parents’ psychologica...

background programs to improve the pain and health status in illnesses with pain such as headache are still in their infancy. mindfulness-based stress reduction (mbsr) is a new psychotherapy that appears to be effective in treating chronic pain. objectives this study evaluated efficacy of mbsr in improving pain severity and mindful awareness in patients with tension headache. conclusions mbsr c...

background type of personality and emotional intelligence affects a person’s mental function and capabilities, which can influence academic achievement. objectives this study was designed to evaluate the relationship between emotional intelligence, type of character and academic achievement. materials and methods this is a cross-sectional study on students of kashan university of medical scienc...

the aim of this study was to find out whether there is seasonality of month of birth in children with diabetes in mashhad and if so whether it differs from that of general papulation. 161 children and adolescents (0-18 years) with type 1 diabetes born between 1983-2001 were included the study. the results were analyzed by student’s t test and chi-square test and a p value<0.05 was considered si...

introduction: diabetes mellitus and osteoporosis are two frequent medical conditions with an increasing prevalence in elderly. this study is conducted to evaluate osteoporosis in postmenopausal females with type 2 diabetes mellitus in sanandaj, the provincial center of kurdistan province in the west of iran. methods: from an initial population of 2500 women with type 2 diabetes, 242 postmenopau...