PURPOSE This study was conducted to evaluate the role of tumor volume in excision of pituitary adenomas. MATERIALS AND METHODS A total of 20 patients with pituitary adenoma underwent surgical excision of the tumor by endonasal transsphenoidal approach. RESULTS A preoperative tumor volume of more than 5 mL is associated with a 90.90% probability of residual tumor (P < .05, statistically sign...

Magnetic resonance imaging reveals heterogeneous regions within high-grade gliomas, such as a contrast-enhanced rim, a necrotic core, and non-contrast-enhanced abnormalities. It is unclear which of these regions best describes tumor aggressiveness. We hypothesized that the vascular leakage volume, reflecting disorganized angiogenesis typical of glioblastoma, would be a strong predictor of clini...

OBJECTIVES Although T stage is an important prognostic tool for oral tongue cancer, it fails to define the depth of invasion and true three-dimensional volume of primary tumors. The purpose of this paper is to determine the relations between tumor volume and lymph node metastasis and survival in early oral tongue cancer. METHODS Forty-seven patients with T1-2 tongue cancer were included. Tumo...

OBJECTIVE To investigate the chemopreventive effect of the hexane extract of Ardisia crispa during the peri-initiation phase of mouse skin tumorigenesis. MATERIALS AND METHODS This study was conducted for 12 weeks on two-stage 7,12-dimethylbenz(α)-anthracene (DMBA)-induced tumor initiation followed by croton-oil-induced tumor promotion in mice. A. crispa root hexane extract (ACRH) was applied...

The metabolic tumor volume (MTV) is the volume of metabolically-active tumor on PET/CT. Although its potential clinical value has been investigated in many cancers, its routine use has been hampered by the delineation method used to calculate the tumor volume. This may be especially difficult for fuzzyPET images. Previous studies have used a lot of approaches for delineation of tumor volume; ho...

Purpose: Previous studies have demonstrated a negative correlation between prostate volume and biopsy yield. By decreasing prostate volume, 5α-reductase inhibitors may enhance cancer detection, which may explain the greater detection of high-grade tumors in the finasteride arm of the Prostate Cancer Prevention Trial (PCPT). Materials and Methods: A mathematical model was constructed analyzing t...

Introduction: As a physical treatment, electrochemical therapy (ECHT) has provided an effective and useful  approach  for  treating  localized  tumors.  The  chemical  changes  due  to  a  direct  electric  current  destroy  the  tumor. This study evaluates the effect of electrical dose and polarity on the efficacy of the treatment of a  colon tumor model.  Materials and Methods: In order to in...