The new WHO guidelines for the treatment on Tuberculosis (4th edition) has come out in 2010 with several important changes from the previous guideline published in 2003.1 Major progress in global TB control follows the wide spread implementation of DOTs strategy. In 2006 stop TB strategy was launched with the objective of (i) universal access to patient centred treatment and protection of popul...

  About 15 % of all musculoskeletal tuberculosis (TB) have hip involvement. Early anti-tubercular drug therapy and other conservative treatment including short-term traction and mobilization programs could prevent hip joint destruction. Reactivation of TB accounts for a significant of active TB incidence, especially in the developed countries with a low TB prevalence. The risk of TB activation ...

Tuberculosis (TB) is a communicable disease caused by the bacillus Mycobacterium tuberculosis and leading cause of death single infectious agent overall. According to WHO Global TB Report, India contributes 26% global burden TB. Currently, four-drug regimen comprising Rifampicin, Isoniazid, Pyrazinamide, Ethambutol approved for treatment drug-sensitive The management cutaneous adverse drug reac...

This non-concurrent cohort study aims to identify predictors of tuberculosis mortality in a large population database in Brazil. Tuberculosis, death, and TB/HIV cases were validated respectively from the tuberculosis surveillance (SINAN/TB), mortality (SIM), and SINAN/AIDS databases for a five-year period. Analysis included proportional hazard models with relative risk estimates. Out of 5,451 i...

dear editor-in-chief we read with interest the study by khazaei et al. (1) in which the authors have nicely concluded that pcr is more sensitive test than ziehl-neelsen staining and histo-pathological examination for the diagnosis of tuberculosis (tb). they have rightly pointed to use pcr, selectively, in acidfast bacilli negative paucibacillary forms of tb. however, we intend to highlight few ...

According to the World Health Organization (WHO) data presented in November 2011, one third of the world's population was infected with the TB bacillus. The incidence of new TB cases in 2010 was 9.5 million with 14 million prevalent cases, most of which occurred in the South-East Asia region. The chief aim of the study was to show the spread of tuberculosis (TB) on renal and bone systems. Also,...

Tuberculosis (TB) is a major cause of childhood morbidity and mortality worldwide. The aim of this review is to describe the management of the child with TB and latent tuberculosis infection (LTBI). To develop this article, a working group reviewed relevant epidemiological and other scientific studies and established practices in conducting LBTI and TB in children. The article describes how to ...

Tuberculosis (TB) is an ancient disease with an enormous global impact. Despite declining global incidence, the diagnosis, phenotyping, and epidemiological investigation of TB require significant clinical microbiology laboratory resources. Current methods for the detection and characterization of Mycobacterium tuberculosis consist of a series of laboratory tests varying in speed and performance...

Disseminated tuberculosis (TB) refers to involvement of two or more non-contiguous sites. It is a common mode of presentation of tuberculosis in patients both with and without HIV/AIDS in India. However, the presence of primary drug resistance in disseminated tuberculosis involving only the extrapulmonary sites in an immunocompetent adult is rare. Extrapulmonary TB accounts for approximately 15...