We describe the implementation of a mandatory tuberculosis (TB) screening program that uses symptom screening and tuberculin skin testing in homeless shelters. We used the results of DNA fingerprinting of Mycobacterium tuberculosis isolates to evaluate the effect of the program on TB incidence and transmission. After the program was implemented, the proportion of cases among homeless persons de...

it is assumed that about 10% of individuals infected with mycobacterium tuberculosis develop tuberculosis. the rate of tuberculosis in solid organ transplant recipients has been estimated to be 50-fold higher than in the general population. candidates for solid organ transplantation are routinely screened for latent tuberculosis infection (ltbi). in this study we aimed to compare tuberculin ski...

RATIONALE Gold miners in South Africa undergo annual radiological screening for tuberculosis in an occupational health center of a gold mining company, but the optimal screening algorithm is unclear. OBJECTIVES To evaluate methods for active case detection of tuberculosis. METHODS A sequential sample of miners attending annual medical examination was screened for tuberculosis using a sympto...

AlL positive diagnosis of active pulmonary tuberculosis can be made only on obtaining a positive sputum or gastric culture for M tuberculosis. The chest x-ray film and tuberculin skin test1 have been used as screening methods. During the third year after the introduction of the acetylcysteine method of digestion at our facility,* 40 cases of active tuberculosis with chest x-ray films read as ne...

Fluoroquinolones are a key component of multidrug-resistant tuberculosis treatment. We describe the first reported case of probable levofloxacin-associated intracranial hypertension in a 6-year-old girl with pulmonary multidrug-resistant tuberculosis. The case highlights the potential risk of secondary intracranial hypertension in multidrug-resistant tuberculosis patients who require prolonged ...

Background At present of the limitation of the current case finding strategies and the global urgency to improve tuberculosis (TB) case finding, a renewed interest in active case finding (ACF) has risen. World Health Organization (WHO) calls for research on TB screening among low-income countries because of the limitation of the passive case finding strategies. We aimed to evaluated Active Case...

BACKGROUND Travelers to countries with high tuberculosis incidence can acquire infection during travel. We sought to compare four screening interventions for travelers from low-incidence countries, who visit countries with varying tuberculosis incidence. METHODS Decision analysis model: We considered hypothetical cohorts of 1,000 travelers, 21 years old, visiting Mexico, the Dominican Republi...

OBJECTIVE To assess the cost effectiveness of the Find and Treat service for diagnosing and managing hard to reach individuals with active tuberculosis. DESIGN Economic evaluation using a discrete, multiple age cohort, compartmental model of treated and untreated cases of active tuberculosis. SETTING London, United Kingdom. Population Hard to reach individuals with active pulmonary tubercul...