Observers were presented with a set of 216 simulated approaching textured baseballs in random order. In Experiment 1 each had a different combination of time to passage (TTP), direction of motion in depth (dMID) in the vertical plane and total change in angular size (Deltatheta). In Experiments 2 and 3 each had a different combination of TTP, dMID and rate of ball rotation (RR). When required t...

Prostate cancer is a major cause of mortality in men in developed countries. It has been reported that the naturally occurring antioxidant α-tocopherol (vitamin E) attenuates prostate cancer cell proliferation in cultured cells and mouse models. We hypothesized that overexpression of the tocopherol transfer protein (TTP), a vitamin E-binding protein that regulates tocopherol status, will sensit...

The pathologic hallmarks of thrombotic thrombocytopenic purpura (TTP) include endothelial cell proliferation and subendothelial hyalin deposits in the microvasculature leading to symptomatic thrombotic occlusions. Plasma or sera from three consecutive patients with TTP were subjected to multiple analyses to determine whether they induce endothelial injury and/or platelet activation, two pathoge...

As smart cities and nations are fast becoming a reality, so does the underpinning infrastructure, such as grids. One particular challenge associated with grid implementation is need to ensure privacy preserving multisubset data aggregation. Existing approaches generally require collaboration of trusted third party (TTP), which may not be practical. This also increases threat exposure, attacker ...

JAPI • VOL. 51 • JULY 2003 smear shows red cell fragments, schistocytes, and helmet cells suggestive of hemolysis. Other features suggestive of MAHA are reticulocytosis, indirect hyperbilirubinina, hemoglobinuria, nucleated red cells and increased LDH. Coagulation parameters are normal except increased FDP. Histopathology shows hyaline thrombi and microthrombi in arterioles and capillaries. Mor...

Alkylation of iridium 5,10,15,20-tetrakistolylporphyrinato carbonyl chloride, Ir(ttp)Cl(CO) (1), with 1°, 2° alkyl halides was achieved to give (ttp)Ir-alkyls in good yields under air and water compatible conditions by utilizing KOH as the cheap reducing agent. The reaction rate followed the order: RCl < RBr < RI (R = alkyl), and suggests an SN2 pathway by [Ir(I)(ttp)](-). Ir(ttp)-adamantyl was...

Large and unusually large von Willebrand factor (vWf) multimers may be responsible for systemic platelet aggregation in thrombotic thrombocytopenic purpura (TTP). This possibility is supported by studies that show deficient vWf-cleaving metalloproteinase and increased platelet-vWf binding during TTP episodes. In acute idiopathic TTP, decreased vWf metalloproteinase is the result of autoantibodi...

Endogenous carbon monoxide (CO) exerts anti-inflammatory effects. Tristetraprolin (TTP) is known to destabilize pro-inflammatory transcripts. Here we found that exogenous CO enhanced the decay of TNF-α mRNA and suppressed TNF-α expression in LPS-activated macrophages from wild-type (WT) mice. However, TTP deficiency abrogated the effects of exogenous CO. While CO treatment prior to DSS administ...

Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening hematological abnormality characterized by thrombocytopenia and microangiopathic hemolytic anemia, with neurological abnormalities and/or renal disease. TTP has been rarely reported in juvenile systemic lupus erythematosus (JSLE) patients and, to our knowledge, its prevalence in a paediatric lupus population has not been s...

TTP/A is the fieldbus protocol of the Time Triggered Architecture (TTA). It provides periodic transmission of realtime data and allows for on-line configuration, diagnostics, and maintenance by use of an interface file system. It is well integrated with the TTP/C protocol and is designed to meet the requirements of a low-cost sensor/actuator bus. TTP/A is a master-slave protocol where the maste...