BACKGROUND Cardiac troponin-T is a sensitive marker of myocardial damage. In a prospective study, the effect of 2 different pH strategies during cardiopulmonary bypass on ischemic myocardial injury and clinical outcome was measured in a pediatric population. METHODS AND RESULTS One hundred one patients (31 neonates 13.2+/-8.3 days and 70 children 34.5+/-44.1 months of age) undergoing open-hea...

[PDF] [Full Text] [Abstract] , June 16, 2005; 22 (1): 1-7. Physiol Genomics T. E. Gillis, B. Liang, F. Chung and G. F. Tibbits troponin C Increasing mammalian cardiomyocyte contractility with residues identified in trout [PDF] [Full Text] [Abstract] , August 15, 2007; 583 (1): 337-350. J. Physiol. K. L. Kreutziger, T. E. Gillis, J. P. Davis, S. B. Tikunova and M. Regnier activation in rabbi...

OBJECTIVE To determine whether a single blood test for the measurement of C reactive protein, or troponin I or T concentrations could be used to stratify patients with intractable unstable angina awaiting transfer for coronary angiography by correlating these values with coronary anatomy and transient myocardial ischaemia. DESIGN Prospective study. SETTING Tertiary cardiac unit. PATIENTS ...

BACKGROUND Serum troponin elevation, characteristic of ischemic myocardial injury, has been observed in some acute ischemic stroke (AIS) patients. Its cause and significance are still controversial. The purpose of this study is to find determinants of troponin elevation and its relationship with stroke severity and location. METHODS Between January 2013 and August 2013, 114 consecutive AIS pa...

Animals have frequently been used as models for human disorders and mutations. Following advances in genetic testing and treatment options, and the decreasing cost of these technologies in the clinic, mutations in both companion and commercial animals are now being investigated. A recent review highlighted the genes associated with both human and non-human dilated cardiomyopathy. Cardiac tropon...

BACKGROUND Cardiac troponin provides diagnostic and prognostic information in acute coronary syndromes, but its role in acute decompensated heart failure is unclear. The purpose of our study was to describe the association between elevated cardiac troponin levels and adverse events in hospitalized patients with acute decompensated heart failure. METHODS We analyzed hospitalizations for acute ...