Abstract Quadruple collaboration has risen rapidly in place of the traditional triple helix model institutional between universities, governments, and companies. Loet Leydesdorff Helen Lawton Smith (2022) approach this challenge by aiming to resolve issue evaluating analyzing various quadruple n-tuple helices. This article seeks recognize increasing complexity new developing issues helices as a...

The Asia-Pacific Consensus Conference was convened to review and synthesize the most current information on Helicobacter pylori management so as to update the previously published regional guidelines. The group recognized that in addition to long-established indications, such as peptic ulcer disease, early mucosa-associated lymphoid tissue (MALT) type lymphoma and family history of gastric canc...

INTRODUCTION Helicobacter pylori (H. pylori) is a Gramnegative, spiral, and microaerophilic bacterium, which can usually persist lifelong in gastric mucosa if not treated efficiently. H. pylori infection plays an undeniable role in the development of different gastroduodenal diseases, while its eradication cures ulcer disease and also prevents occurrence of gastric cancer (1–3). At the beginnin...

PURPOSE The efficacy of EMG-biofeedback and low-frequency electrical stimulation for the treatment of anal incontinence has not been proven. Our purpose was to evaluate a novel therapeutic concept, termed triple target treatment, which combines amplitude-modulated medium-frequency stimulation and EMG-biofeedback. METHODS Patients with anal incontinence were randomly assigned to the triple tar...

Tools for Practice articles in Canadian Family Physician are adapted from articles published twice monthly on the Alberta College of Family Physicians (ACFP) website, summarizing medical evidence with a focus on topical issues and practice-modifying information. The ACFP summaries and the series in Canadian Family Physician are coordinated by Dr G. Michael Allan, and the summaries are co-author...

As an exceedingly recalcitrant and highly aggressive tumor type without Food and Drug Administration-approved treatment or a known cure, the prognosis of recurrent extensive stage platinum-resistant/refractory small cell lung cancer (SCLC) is worse than other types of lung cancer, and many other tumor types, given a response rate of less than 10% and an overall survival of less than six months....

Malic enzymes have high cofactor selectivity. An isoform-specific distribution of residues 314, 346, 347 and 362 implies that they may play key roles in determining the cofactor specificity. Currently, Glu314, Ser346, Lys347 and Lys362 in human c-NADP-ME were changed to the corresponding residues of human m-NAD(P)-ME (Glu, Lys, Tyr and Gln, respectively) or Ascaris suum m-NAD-ME (Ala, Ile, Asp ...

helicobacter pylori infection is a prevalent disease among iranian children. the purpose of this study was to compare the effect of ciprofloxacin and furazolidone on eradicating helicobacter pylori in iranian children in combination with amoxicillin and omeprazole. in this cohort study, helicobacter pylori infection was confirmed by gastroscopy, rapid urease test or pathologic assessments. a to...

Purpose: No consensus is made for preoperative skin antisepsis upper extremity surgery. We aimed to determine if the use of povidone-iodine only (single regimen) instead and alcohol-chlorhexidine (triple resulted in an increased rate surgical site infection (SSI), detect any associated factors that risk.Methods: A cross-sectional, retrospective review medical records was patients who underwent ...

The following definition of resistant hypertension is proposed: Provided that adherence to the regimen can be assured, hypertension should be considered resistant if the blood pressure cannot be reduced to less than 150/100 mm Hg by a rational triple drug regimen, including a diuretic, prescribed in nearly maximal doses and if the pretreatment blood pressure was greater than or equal to 180/115...