BACKGROUND The timing of maternal weight change in pregnancy may be an important determinant of the newborn's size. OBJECTIVE The purpose was to identify effects of maternal weight change by trimester on newborn size, under the hypothesis that low weight gain early in pregnancy predicts proportionately smaller newborns. DESIGN Women planning to become pregnant were followed by clinic visits...

It seems appropriate to use propylthiouracil to treat maternal hyperthyroidism during the first trimester of pregnancy. We present the case of a 26-year-old woman with acute liver failure associated with propylthiouracil during the first trimester of pregnancy. She was successfully treated without liver transplantation. Attention should be paid to the possible occurrence of propylthiouracil-ind...

background: measuring of maternal serum pregnancy-associated plasma protein-a (papp-a) in first trimester can be a way for early detection of adverse prenatal outcome due to faulty placenta.objective: the aim was to determination of association between placental thickness in second trimester with low level of papp-a in first trimester.materials and methods: in this cohort study, serum papp-a of...

OBJECTIVES To assess use of antiretroviral therapy (ART) by HIV positive pregnant women in London since 1994 and the risk of congenital abnormalities associated with multidrug exposure during the first trimester of pregnancy. METHODS Retrospective multicentre study of medical, obstetric, and paediatric notes of all mother-infant pairs, where the mother was known to be HIV infected before deli...

Women with preeclampsia, independent of obesity and glucose intolerance, exhibit insulin resistance during pregnancy. The purpose of the present study is to determine whether early diagnosis of insulin resistance during pregnancy can predict preeclampsia. Through a case-control study, 675 pregnant women were selected and their first trimester blood was taken. Their fasting blood glucose and ins...

BACKGROUND The government is encouraging the adoption of electronic medical records (EMRs). There is little information about using EMRs in the obstetric literature and none about using them in family medicine residencies. Our purpose was to assess if using an EMR was associated with improvement in the ordering and availability of prenatal tests. METHODS A retrospective chart review comparing...

BACKGROUND Measuring of maternal serum pregnancy-associated plasma protein-A (PAPP-A) in first trimester can be a way for early detection of adverse prenatal outcome due to faulty placenta. OBJECTIVE The aim was to Determination of association between placental thickness in second trimester with low level of PAPP-A in first trimester. MATERIALS AND METHODS In this cohort study, serum PAPP-A...

BACKGROUND The objective of this study was to evaluate the clinical outcomes and to discuss the management of women presenting with an invasive cervical cancer during pregnancy. PATIENTS AND METHODS We retrospectively reviewed patients treated for an invasive cervical cancer diagnosed during pregnancy between 1985 and 2000 in our institution. RESULTS Twenty-one pregnant patients among a tot...