Two probes consisting of vitamin B(12) (CNCbl) conjugated to Gd chelates by esterification of the ribose 5'-OH moiety, Gd-DTPA-CNCbl (1; DTPA = diethylenetriamine-N,N,N',N'',N''-pentaacetic acid) and Gd-TTHA-CNCbl (2; TTHA = triethylenetetramine-N,N,N',N'',N''',N'''-hexaacetic acid), have been synthesised and characterised. The crystal structure of a dimeric form of 1, obtained by crystallisati...

Ubiquitin activating enzyme E1 plays a pivotal role in ubiquitin based protein signaling through regulating the initiating step of the cascade. Previous studies demonstrated that E1 is inhibited by covalent modification of reactive cysteines contained within the ubiquitin-binding groove and by conditions that increase oxidative stress and deplete cellular antioxidants. In this study, we determi...

The secondary amines found in b-PIBSI dispersants prepared by attaching two polyisobutylene chains to a polyamine core via two succinimide moieties were reacted with ethylene carbonate (EC). The reaction generated urethane bonds on the polyamine core to yield the modified b-PIBSI dispersants (Mb-PIBSI). Five dispersants were prepared by reacting 2 molar equivalent (meq) of polyisobutylene termi...

Abstract This study contributes to the current state of knowledge by highlighting physical–chemical interactions between biochar and dyes. The removal Acid Orange 7 (AO7) dye a modified obtained from wastes mandarin peels (MPs) has been investigated in this work. A dehydration procedure with 80% H 2 SO 4 under reflux was applied produce an innovative MPs then boiled O followed boiling triethyle...