2-Methyl-8-quinolinol and sixteen 5-, 7-, and 5,7-substituted derivatives with fluoro, chloro, bromo, iodo, nitro, and amino substituents were tested for in vitro antifungal activity against five fungi, Aspergillus niger, A. oryzae, Trichoderma viride, Myrothecium verrucaria, and Trichophyton mentagrophytes. The 5,7-dichloro and 5,7-dibromo derivatives were the most fungitoxic of the compounds ...

Onychomycosis is the most common nail infective disorder. It is caused mainly by anthropophilic dermatophytes, in particular by Trichophyton rubrum and T. mentagrophytes var. interdigitale. Yeasts, like Candida albicans and C. parapsilosis, and molds, like Aspergillus spp., represent the second cause of onychomycosis. The clinical suspect of onychomycosis should be confirmed my mycology. Onycho...

A n t i f u n g a l a c t i v i t y o f r h e i n ( 1 , 8 dihydroxyanthraquinone3carboxylic acid) isolated from the ethyl acetate extract of Cassia fistula flower was studied. Rhein inhibited the growth of many fungi such as Trichophyton mentagrophytes (MIC 31.25 μg/ml), Trichophyton simii (MIC 125 μg/ml), Trichophyton rubrum (MIC 62.5 μg/ml) and Epidermophyton floccosum (MIC 31.25 μg/ml).

Los diferentes microorganismos que componen la microbiota normal de las aves, pueden estar presentes en elementos y ambientes, situaciones donde un hospedero se ve inmunocomprometido o susceptible, provocar presencia enfermedades, ya sea animales domésticos humanos. Entre los agentes micóticos aislados frecuentemente aves encuentran: Aspergillus spp., Cryptococcus Candida Microsporum spp. Malas...

Background and Purpose: Trichophyton quinckeanum, a known zoophilic dermatophyte responsible for favus form in rodents camels, is occasionally reported to cause human infections. Case Report: This study aimed report case of tinea corporis caused by T. quinckeanum that experienced annular erythematous pruritic plaque with abundant purulent secretions. In June 2021, 15-year-old girl an cup shape ...

The antibacterial agent mupirocin (pseudomonic acid A) is used as a topical agent in the treatment of superficial infections by Gram-positive bacteria, particularly Staphylococcus aureus. However, we demonstrate here that the compound also inhibits the growth of a number of pathogenic fungi in vitro, including a range of dermatophytes and Pityrosporum spp. It inhibited the incorporation of amin...

Most of the fungal species that infect humans can grow in more than one morphological form but only a subset of pathogens produce filamentous hyphae during the infection process. This subset is phylogenetically unrelated and includes the commonly carried yeasts, Candida albicans, C. dubliniensis, and Malassezia spp., and the acquired pathogens, Aspergillus fumigatus and dermatophytes such as Tr...

The antifungal activities of several solanum alkaloids and their derivatives were examined against a variety of fungal strains such as Candida albicans and Trichophyton spp. Solacongestidine (I) showed the strongest activity (minimum inhibitory concentration) against C. albicans (0.8 ƒÊg/ml), T. rubrum (0.4 ƒÊg/ml) and Cryptococcus albidus (0.78 ƒÊg/ml), and also showed lesser activities agains...

Knowledge of epidemiological and mycological characteristics of onychomycosis has been noted by many authors as being an important tool for control of these fungal infections. This study seeks to improve knowledge of onychomycosis epidemiology and mycological features. Samples were taken from infected fingernails and toenails of 976 patients undergoing treatment at a respected Dermatology Cente...

White superficial onychomycosis is less common than distal subungual onychomycosis and occurs when certain fungi invade the superficial layers of the nail plate directly. Later, the infection may move through the nail plate to infect the cornified layer of the nail bed and hyponychium. It can be recognized by the presence of welldelineated opaque “white islands” on the external nail plate, whic...