Infections with the sexually transmitted protozoan Trichomonas vaginalis are usually treated with metronidazole, a 5-nitroimidazole drug derived from the antibiotic azomycin. Metronidazole treatment is generally efficient in eliminating T. vaginalis infection and has a low risk of serious side effects. However, studies have shown that at least 5% of clinical cases of trichomoniasis are caused b...

The effect of temperature as a possible factor on the survival of Trichomonas vaginalis for shipment or routine laboratory maintenance was studied. Ten strains of T. vaginalis, ATCC 30001, ATCC 30238, and eight clinical isolates, were examined for viability when kept incubated at 37 degrees C or removed from this temperature and held at 42, 22, or 5 degrees C for increasing lengths of time with...

background: the interaction between hiv and trichomonas vaginalis infection has been widely studied in most developed countries but with scanty information in sub-saharan africa. while many of these studies have examined the prevalence of t. vaginalis infection in hiv positive individuals, no study in nigeria has shown the effect of t. vaginalis on hiv transmission. therefore, the study aimed t...

Bacterial vaginosis, trichomoniasis, and genital candidiasis are considered the main etiologies of vulvovaginitis. Few studies estimate the prevalence of vulvovaginitis among adolescents, especially in Brazil. This study aimed to determine the prevalence and main risk factors associated with bacterial vaginosis and genital infection by C. albicans and Trichomonas vaginalis among a group of adol...

Trichomonas vaginalis is a pathogen that triggers severe immune responses in hosts. T. vaginalis α-actinin 2, Tvα-actinin 2, has been used to diagnose trichomoniasis. This study was undertaken to examine the role of Tvα-actinin 2 as an antigenic molecule to induce immune responses from humans. Western blot analysis using anti-Tvα-actinin 2 antibodies indicated its presence in the secreted prote...

* Paper read at the European Symposium of the I.U.V.D.T. at Cracow, Poland. in Sevtember, 1960. female and 28 male patients were inoculated on several bacterial media, as well as on Sabouraud's maltose agar; the yeast-like fungi were identified according to routine mycological procedures. The diagnosis of Trichomonas vaginalis infestation was made in all cases by the dark-field and phase-contra...

After a recent report showing the in vitro susceptibility to mebendazole of a strain of Trichomonas vaginalis that was resistant to metronidazole, we present two cases of metronidazole resistant infection, both of which failed to respond to oral mebendazole.

* Paper read at the European Symposium of the I.U.V.D.T. at Cracow, Poland. in Sevtember, 1960. female and 28 male patients were inoculated on several bacterial media, as well as on Sabouraud's maltose agar; the yeast-like fungi were identified according to routine mycological procedures. The diagnosis of Trichomonas vaginalis infestation was made in all cases by the dark-field and phase-contra...

Shape variations of strains of Trichomonas vaginalis were demonstrated by scanning electron microscopy (SEM) following inoculation on McCoy cell monolayers and after interaction with human erythrocytes. The parasites adhered to both cells and presented amoeboid forms, with pseudopodia-like extensions. Several amoeboid organisms swam freely over the cell monolayers and produced aggregates. These...