Antipsychotic drugs are widely used in the treatment of schizophrenia and psychotic disorder. The lack of antipsychotic response and treatment-induced side-effects, such as neuroleptic syndrome, polydipsia, metabolic syndrome, weight gain, extrapyramidal symptoms, tardive dyskinesia or prolactin increase, are the two main reasons for non-compliance and increased morbidity in schizophrenic patie...

Locoregional failure occurs in approximately 25-50% of patients with head and neck squamous cell carcinoma (HNSCC), who are treated with chemoradiotherapy (CRT). Timely identification of treatment failure allows salvage surgery to be undertaken. Imaging the posttreatment neck therefore has an important role for the early identification of a residual/recurrent tumours while also preventing unnec...

we evaluated the effect of vitamin e and metformin on fatty liver disease in obese children.this interventional study has been done on 119 children with non-alcoholic fatty liver disease (based on sonography results). patients were divided into four treatment groups; they received metformin 1gr daily (age 12 years), vitamin e 800 u daily and vitamin e 400 u daily. liver sonography was performed...

micrornas (mirnas) represent a class of small non-coding rna molecules that regulate gene expression at the post-transcriptional level. they play a crucial role in diverse cellular pathways. ionizing radiation (ir) is one of the most important treatment protocols for patients that suffer from cancer and affects directly or indirectly cellular integration. recently it has been discovered that mi...

introduction: malaria is a protozoal disease, transmitted to humans by female anopheles mosquito bite. plasmodium falciparum, compared to other kinds of plasmodium, causes more severe malaria and is associated with a higher mortality rate. annually, one to three million deaths occur due to malaria, especially by p. falciparum. case presentation: in this report, we introduce an iranian patient s...

background: patients with symptomatic malignant pleural effusion (mpe) may gain profit from pleurodesis for relief of dyspnea and in preventing the accumulation of fluid or air in the pleural space. pleurodesis methods are palliative and regard the patient's symptoms and underlying disease condition that are different. the purpose of this study was to assess the efficacy of bleomycin in th...

This article provides a rationale for considering predictors of growth in a treatment group as inadequate to identifying predictors of treatment response. When we interpret predictors of growth in a treatment group as synonymous with predictors of treatment response, we implicitly attribute all of the treated children's growth to the treatment, an untenable assumption under most conditions. We ...