Software effort estimates is an important part of software development work and provides essential input to project feasibility analyses, bidding, budgeting and planning. Analogy-based estimates models emerge as a promising approach, with comparable accuracy to arithmetic methods, and it is potentially easier to understand and apply. Studies show all the models are sensitive to the quality and ...

Adaptive designs for clinical trials have the potential to improve the efficiency of clinical research by, for instance, seamlessly combining different stages of a clinical development programme. Adaptive seamless designs (ASD) combining phases II and III with adaptations such as treatment or subgroup selection are becoming increasingly widely used. The work required to develop application spec...

Software architecture allows us to make many decisions about a software system and analyze it even before it has been implemented, so as to make planned development possible. Similarly, architecture-based software evolution planning makes planned evolution possible by allowing us to make many decisions about the evolution of a software system and to analyze its evolution at the level of archite...

BACKGROUND The old Treatment Planning Systems (TPSs) used for intracavitary brachytherapy with Cs-137 Selectron source utilize traditional dose calculation methods, considering each source as a point source. Using such methods introduces significant errors in dose estimation. As of 1995, TG-43 is used as the main dose calculation formalism in treatment TPSs. OBJECTIVES The purpose of this stu...

this paper presented a mixed integer programming for integrated scheduling and process planning. the presented process plan included some orders with precedence relations similar to multiple traveling salesman problem (mtsp), which was categorized as an np-hard problem. these types of problems are also called advanced planning because of simultaneously determining the appropriate sequence and m...

Considering user preferences is a determining factor in optimizing the value of a software release. This is due to the fact that user preferences for software features specify the values of those features and consequently determine the value of the release. Certain features of a software however, may encourage or discourage users to prefer (select or use) other features. As such, value of a sof...

Software development is a complicated process and requires careful planning to produce high quality software. In large software development projects, release planning may involve a lot of unique challenges. Due to time, budget and some other constraints, potentially there are many problems that may possibly occur. Subsequently, project managers have been trying to identify and understand releas...