Widespread use of human umbilical cord cells for cardiovascular tissue engineering requires production of large numbers of well-characterized cells under controlled conditions. In current research projects, the expansion of cells to be used to create a tissue construct is usually performed in static cell culture systems which are, however, often not satisfactory due to limitations in nutrient a...

The removal of trace organic compounds (TrOCs) by a novel membrane distillation-thermophilic bioreactor (MDBR) system was examined. Salinity build-up and the thermophilic conditions to some extent adversely impacted the performance of the bioreactor, particularly the removal of total nitrogen and recalcitrant TrOCs. While most TrOCs were well removed by the thermophilic bioreactor, compounds co...

A stirred tank bioreactor (STB) integrated with an expanded bed adsorption (EBA) system containing anion-exchange resin (Diaion WA30) was developed for in situ removal of acetate to increase the production of α-interferon-2b (α-PrIFN-2b) by Escherichia coli (E. coli). Although the total acetate (9.79 g/L) secreted by E. coli in the integrated STB/EBA system was higher than that in a bioreactor ...

Cell physiology dynamically affects the nutrient requirements of a culture. It is critical to obtain data over appropriate time intervals to assess the impact of process conditions on the cell population. By optimizing bioreactor operation, feed strategies and media composition, we can limit the number of experiments to obtain the empirical data sets. For this poster, we present an emerging pro...

Tissue engineering is an emerging technology to replace tissues and organs damaged due to trauma of disease with fully functional living tissue equivalents. Tissue development is facilitated by bioreactors, devices engineered to deliver appropriate spatial and temporal nutrient transport and mechanical loading in a welldefined and controlled environment. Bioreactors that provide well-defined an...

Nowadays distillation is recognized as one of the economical and the most trustable separation methods in chemical, petroleum, gas and petrochemical industries. It is almost used as a first and the most applicable choice in separation methods. In this article the effect of inlet downcomer on the hydrodynamics of industrial sieve tray has been elaborated. The study was carried out by using a 3-D...

In this work, we study optimal and suboptimal control strategies for the treatment of a polluted water resource by using aside a continuous bioreactor. The control consists in choosing the inlet volumetric flow rate for filling the bioreactor with contaminated water from a considered resource (lake, reservoir, watertable...). The treated outflow returns to the resource. We tackle an optimizatio...

This review presents a general overview of physical, chemical and biological waste-gas treatment techniques such as adsorption, absorption, oxidation and biodegradation, focusing more extensively on combined processes. It is widely recognized that biological waste-gas treatment devices such as biofilters and biotrickling filters can show high performance, often reaching removal efficiencies abo...

The performance of a hybrid bubble column/biofilter (HBCB) bioreactor for the removal of dichloromethane (DCM) from waste gas streams was studied in continuous mode for several months. The HBCB bioreactor consisted of two compartments: bubble column bioreactor removing DCM from liquid phase and biofilter removing DCM from gas phase. Effect of inlet DCM concentration on the elimination capacity ...