Background Post-traumatic stress disorder (PTSD) is a severe anxiety disorder that affects a substantial portion of combat veterans and poses serious consequences to long-term health. Consequently, the identification of diagnostic and prognostic blood biomarkers for PTSD is of great interest. Previously, we assessed genome-wide gene expression of seven brain regions and whole blood in a social ...

Recent geopolitical events, including the terrorist attacks on the United States on September 11, 2001, and ongoing military operations in Iraq, have raised awareness of the often severe psychological after-effects of these and other types of traumatic events. Post traumatic stress disorder (PTSD) represents the most severe of these sequelae. PTSD is an under-recognized and under-treated chroni...

BACKGROUND History of traumatic experience is common in dissociative disorder (DD), and similarity of symptoms and characteristics between DD and posttraumatic stress disorder (PTSD) encouraged to consider DD as trauma-related disorder. However, conceptualization of DD as a trauma-related syndrome would critically affect diagnosis and treatment strategies. The present study addressed overlap an...

background post-traumatic stress disorder (ptsd) comprises a collection of symptoms following exposure to injury-causing accidents of life. it is estimated that the prevalence of ptsd in children with malignancy and their parents is between 10-30% and even several years after treatment of malignancy this disorderremain in 20-20% of these patients. objectives this study investigated the prevalen...

Posttraumatic stress disorder (PTSD) is a common and disabling anxiety disorder that may occur in the aftermath of exposure to potentially traumatic life events. PTSD is moderately heritable, but few specific molecular variants accounting for this heritability have been identified. Genes regulating the hypothalamic-pituitary-adrenal (HPA) axis, such as corticotrophin-releasing hormone type 1 re...

although childhood is connected with high neuroplasticity changes, but because of the immaturity of the neural and cognitive systems, it is ready to grow developmental deviations and future susceptibility for neuropsychological disorders. young children face cognitive, emotional, and linguistic limits that may lead them more vulnerable to post-traumatic stress disorder (ptsd). ptsd prevalence d...

BACKGROUND The validity of applying the construct of post-traumatic stress disorder (PTSD) across cultures has been the subject of contention. Although PTSD symptoms have been identified across multiple cultures, questions remain whether the constellation represents a coherent construct with an interpretable factor structure across diverse populations, especially those naïve to western notions ...

Test: The self rating inventory for post-traumatic stress disorder (SRIP) includes 22 items based on DSM-IV criteria for posttraumatic stress disorder (PTSD). Each item is rated on a 4 point scale (1 = not at all to 4 = extremely) and total SRIP scores range from 22 to 88. A score of 52 or above is the advised threshold for diagnosis of PTSD. Separate interviewers administered the SRIP and the ...

Dear Editor, Post-traumatic stress disorder (PTSD) is an anxiety disorder that can arise after exposure to a terrifying event/ordeal in which severe physical harm occurred or was about to happen. PTSD symptoms include persistent re-experience of the trauma, avo idance o f t rauma-assoc ia ted s t imul i , and hyperarousal. In the present report, we describe a woman with PTSD whose symptoms were...

The personal, social and economic burden of post-traumatic stress disorder (PTSD) is high and therapeutic approaches are only partially effective. Therefore, there is an urgent need to understand the cellular and molecular alterations in PTSD brains in order to design more effective treatment strategies. Although brain imaging strategies have considerably improved our understanding of PTSD, the...