Transverse myelitis (TM) is an inflammatory process involving a restricted area of the spinal cord. The usual dramatic presentation makes TM a medical emergency. Early detection and aggressive therapy are required in order to improve the prognosis. The association of this unique clinical phenotype and autoantibody provides circumstantial evidence that an autoimmune aetiology might be involved. ...

Acute transverse myelitis is a rare, focal immune-mediated disease that affects the sensory and motor pathways of the spinal cord. It is characterized by a sudden clinical onset of neurological motor dysfunction associated with sensory loss and autonomic disturbances. The following tetrad of symptoms has been classically described in acute transverse myelitis (ATM): 1) weakness in the arms/legs...

BACKGROUND Transverse myelitis, subarachnoid hemorrhage, and nephropathy are established but rare complications of hepatitis B virus infection that can potentially be triggered by an antibody-mediated vasculitis as a result of a viral infection. The following is a case report detailing a patient presenting with all three of the above presentations who is cytoplasmic antineutrophil cytoplasmic a...

An infectious etiology is one of the postulated mechanisms for autoimmune diseases. An emergence of autoimmune phenomena associated with hepatitis C virus (HCV) infection has been reported. Transverse myelitis is an inflammatory disease of the spinal vasculature attributed to viral infections and to autoimmune diseases including systemic lupus erythematosus and the antiphospholipid syndrome. A ...

Corresponding author: Youn Hee Lim, M.D., Department of Anesthesiology and Pain Medicine, Sanggye Paik Hospital, College of Medicine, Inje University, 761-1, Sanggye 7-dong, Nowon-gu, Seoul 139-707, Korea. Tel: 82-2-950-1173, Fax: 82-2-950-1323, E-mail: [email protected] This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http...

In the last few years, substantial evidence has been provided on peripheral nervous involvement in infection by hepatitis C virus (HCV), whilst central nervous involvement is rare. Here, we report a case of acute transverse myelitis in a woman developing 4 years after documented HCV seropositivity, associated with intrathecal anti-HCV protein IgG. Isoelectrofocusing of all CSF samples before an...

tsutsugamushi bacteria. It is endemic to a part of world known as the “tsutsugamushi triangle” extending from northern Japan and far-eastern Russia in the north, to northern Australia in the south, and to Pakistan and Afghanistan in the west1–2. Scrub typhus has been reported from many parts of India including Himachal Pradesh3. The disease is characterized by fever, headache, myalgia, cough, s...

An otherwise healthy 38-year-old male presented to the Neurology clinic in Annapurna Neurology Institute and Allied Sciences; with the complaint of progressive weakness of both of his lower limbs that began 2 days earlier. Before the onset of weakness; he felt mild pain associated with the tingling sensation from the waist down. Several hours later after that he felt difficulty in passing urine...