OBJECTIVE Cerebrospinal fluid rhinorrhea, pneumocephalus and meningitis are serious complications following transsphenoidal excision of sellar, suprasellar and parasellar lesions. This study evaluates the use of a new bioadhesive, Bioglue as an adjunct in reconstructing the sellar floor and preventing CSF fistula and investigates the possible complications associated with its use. METHODS In ...

Occurrence of symptomatic chronic subdural haematoma (SDH) following transsphenoidal decompression of pituitary adenoma, which needed surgical evacuation, is not reported. Author reports a case of symptomatic chronic subdural haematoma observed in a series of 480-transsphenoidal surgery. A 52-year old female underwent transsphenoidal surgery for pituitary adenoma. She developed cerebrospinal fl...

Objective: This study aims to analyze the complications of endoscopic transsphenoidal surgery for pituitary neoplasms. Methods: 326 patients who underwent neuroendoscopic endonasal transsphenoidal surgery at the neurosurgery department of the First Affiliated Hospital of Chongqing Medical University from July 2012 to July 2015 were enrolled in this retrospective analysis. Results: Among the 326...

Background Transsphenoidal secondary operations are a minority but not rare occurrence. How to viably prevent cerebral fluid (CSF)-related complications and confine surgery-caused injury in surgery as minimally possible is huge challenge. This article shares our solution of recycling prior Hadad-Bassagasteguy flap (HBF) along with using small piece free autologous mucosa reconstruct the skull b...

To assess the effectiveness of continuous lumbar drainage (LD) for management of postoperative cerebrospinal fluid leaks after endoscopic endonasal transsphenoidal approach for resection of pituitary adenoma. Three hundred eighty-four medical records of patients who were admitted to our institute during a 2.5-year period were retrospectively reviewed, 33 of them experienced low-flow cerebrospin...

In this study, we analyze and discuss the treatments of postoperative nasal complications after endonasal transsphenoidal resection of pituitary neoplasms (PNs). We performed 129 endonasal transsphenoidal resections of PNs and analyzed and treated cases with nasal complications. After endonasal transsphenoidal resection of PNs, there were 26 cases of postoperative nasal complications (20.1%), i...

Background Bioabsorbable plates are frequently utilized in the repair of skull base defects following transsphenoidal operations. Traumatic intracranial pseudoaneurysms are a rare complication of transsphenoidal surgery. To date, iatrogenic carotid pseudoaneurysm associated with the use of an absorbable plate has been reported once. Results A 57-year-old man with a large nonfunctional pituitary...

Cerebrospinal fluid (CSF) leak is the most commonly encountered perioperative complication in transsphenoidal surgery for pituitary lesions. Direct closure with a combination of autologous fat, local bone, and/or synthetic grafts remains the standard of care for leaks encountered at the time of surgery as well as postoperatively. The development of the vascularized nasoseptal flap as a closure ...

Cushing disease is caused by excessive adrenocorticotropic hormone (ACTH) production by the pituitary adenoma. Transsphenoidal surgery is its first-line treatment. The incidence of Cushing disease in children and adolescents is so rare that long-term prognoses have yet to be made in most cases. We followed-up on a 16-year-old male Cushing disease patient who presented with rapid weight gain and...

INTRODUCTION It is unclear whether the proportions of remission and the recurrence rates differ between endoscopic transsphenoidal surgery (TS) and microscopic TS in Cushing's disease (CD); thus, we conducted a systematic review and meta-analysis to evaluate studies of endoscopic TS and microscopic TS. METHODS We conducted a comprehensive search of PubMed to identify relevant studies. Remissi...