نتایج جستجو برای: transplacental
تعداد نتایج: 1342 فیلتر نتایج به سال:
Effects of transplacental and trans-breast milk exposure to a foodderived mammary and colon carcinogen, 2-amino-l-methyl-6-phenylimidazo[4,5-¿>]pyridine (PhIP), were investigated in rats. Female SpragueDawley rats were administered PhIP in the diet (100 ppm) for 4 weeks before mating with nontreated males and also during gestation and lac tation. As controls, additional females were maintained...
Severe transplacental lithium toxicity in a neonate is described. There were gross functional lesions of the cardiovascular, renal, and neuromuscular systems with no structural abnormalities. At 1 year of age cardiovascular and renal function is normal, but there is developmental delay.
Dental Faculty University of Malaya Kuala Lumpur, Malaysia possible faecal-oral pathway of spread to man. Infection is also frequently produced by contact with previously contaminated soil, land snails, earthworms, fleas and cock? It is also possible to produce a clinical disease through consumption of raw or incompletely cooked meat." Transplacental infection can also occur if the mother acqui...
Intrauterine and early postnatal life are periods of exceptionally high susceptibility to certain kinds of chemical carcinogens. The most potent known transplacental carcinogens are direct acting alkylating agents. Most nonreactive compounds, which require enzymes for metabolic conversion into chemically reactive "proximate carcinogens," are less effective because the required enzymes are prese...
Although early exposure to environmental pollutants may have important toxicological consequences, the mechanisms of transplacental transfer of synthetic musks are still not well understood. The objective of the present study was to learn the musk contaminations in three matrices, including maternal blood, umbilical cord blood, and breast milk; and investigate their placental transfer mechanism...
The carcinogenicity of safrole following transplacental ex posure of the mouse fetus and exposure of the neonatal mouse via the mother's milk was investigated in C57BL/6J x CSHeB/ FeJ F, (hereafter called B6C3F,) mice by intragastric admin istration of the agent to pregnant and lactating C57BL/6J females. Safrole (120 ftg/g body weight per treatment) was administered to (a) pregnant mice (4 tim...
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