BACKGROUND AND PURPOSE Early diagnosis and treatment of a stroke improves patient outcomes, and knowledge of the cause of the initial event is crucial to identification of the appropriate therapy to maximally reduce risk of recurrence. Assumptions based on historical frequency of ischemic subtypes may need revision if stroke subtypes are changing as a result of recent changes in therapy, such a...

BACKGROUND Novel oral anticoagulants (NOACs) have been shown to be at least as good as warfarin for preventing stroke or transient ischemic attack in patients with atrial fibrillation, yet diffusion of these therapies and patterns of use among atrial fibrillation patients with ischemic stroke and transient ischemic attack have not been well characterized. METHODS AND RESULTS Using data from G...

Visceral artery aneurysms are rarely reported. They can occur in the context of a variety of underlying diseases. These aneurysms may coexist with non-visceral arterial aneurysms.Here we describe an 80-year-old man with concomitant superior mesenteric, celiac, renal, and aorto-bi-iliac aneurysms. The patient was a hypertensive and hyperlipidemic old man with history of transient ischemic attack...

BACKGROUND Patients with ischemic stroke or transient ischemic attack presumably related to patent foramen ovale (PFO) are at risk for recurrent cerebrovascular events. Differences in long-term clinical outcome were investigated among patients with percutaneous PFO closure and those who received medical treatment. METHODS AND RESULTS Between 1994 and 2000, 308 consecutive patients with cerebr...

visceral artery aneurysms are rarely reported. they can occur in the context of a variety of underlying diseases. these aneurysms may coexist with non-visceral arterial aneurysms. here we describe an 80-year-old man with concomitant superior mesenteric, celiac, renal, and aorto-bi-iliac aneurysms. the patient was a hypertensive and hyperlipidemic old man with history of transient ischemic attac...

BACKGROUND AND PURPOSE Early anticoagulation after cardioembolic stroke remains controversial because of the potential for hemorrhagic transformation (HT). We tested the safety and feasibility of initiating rivaroxaban ≤14 days after cardioembolic stroke/transient ischemic attack. METHODS A prospective, open-label study of patients with atrial fibrillation treated with rivaroxaban ≤14 days of...

BACKGROUND AND PURPOSE Perivascular spaces (PVSs) are considered markers of small vessel disease. However, their long-term prognostic implications in transient ischemic attack/ischemic stroke patients are unknown. Ethnic differences in PVS prevalence are also unknown. METHODS Two independent prospective studies were conducted, 1 comprising predominantly whites with transient ischemic attack/i...

Severe internal carotid artery (ICA) stenosis is a common cause of cerebrovascular accident (CVA) in middle-aged patients. Contralateral carotid occlusion (CCO) in patients with severe ICA stenosis is associated with high risk of CVA. Carotid endarterectomy (CEA) is associated with more complications in patients with CCO than those without CCO. In this study, we present the case of a 61-year-ol...

Association of protease inhibitors and ergotamine causing systemic ergotism is well established1,2,3. Cerebral ergotism is poorly reported4,5. We describe the case of an HIV positive 49 yo man under protease inhibitors (ritonavir) presenting with total reversible left hemiparesis after the intake of 3 g of ergotamine. After 20 minutes he was spontaneously asymptomatic. TIA was diagnosed. Parenc...

We used a robotic exoskeleton to quantify specific patterns of abnormal upper limb motor behaviour in people who have had transient ischemic attack (TIA). A cohort of people with TIA was recruited within two weeks of symptom onset. All individuals completed a robotic-based assessment of 8 behavioural tasks related to upper limb motor and proprioceptive function, as well as cognitive function. R...