نتایج جستجو برای: transient focal cerebral ischemic
تعداد نتایج: 409826 فیلتر نتایج به سال:
The reasons why some animal studies indicate that estrogens increase focal cerebral ischemic damage while others show estrogen-induced neuroprotection has hitherto not been fully elucidated. Recent evidence indicates that discrepancies in hormone administration paradigms, resulting in highly different serum hormone concentrations, may account for the dichotomy. The current study aimed to test t...
In a group of 132 patients with transient ischemic attacks ((TIAs) 7 patients (4 men, 3 women, ages 64 to 81) had TIAs preceded by hypotension. The average fall of mean blood pressure during an attack was 26.4 +/- 5.5 mm Hg (SD). Only one of these patients had a TIA which was not preceded by hypotension. This episode occurred during a paroxysm of coughing. All 7 of these patients had hypertensi...
cerebrovascular attack (cva) and transient ischemic attack (tia) are major causes of emergency department visits around the globe. a significant number of these patients may experience repeat attacks if left untreated. several risk stratifying scoring systems have been developed in recent years to point out the high risk patients. abcd 2 is based on age, blood pressure, clinical status, diabete...
BACKGROUND The involvement of the complement system in brain injury has been scarcely investigated. Here, we document the pivotal role of mannose-binding lectin (MBL), one of the recognition molecules of the lectin complement pathway, in brain ischemic injury. METHODS AND RESULTS Focal cerebral ischemia was induced in mice (by permanent or transient middle cerebral artery occlusion) and rats ...
BACKGROUND AND PURPOSE Different strategies for neuroprotection of neonatal stroke may be required because the developing brain responds differently to hypoxia-ischemia than the mature brain. This study was designed to determine the role of caspase-dependent injury in the pathophysiology of pure focal cerebral ischemia in the immature brain. METHODS Postnatal day 7 rats were subjected to perm...
Background: It is well known that the hippocampus, the CA1 Pyramidal cells in particular, is selectively vulnerable during global cerebral ischemia. Recently, it is observed that pentoxifylline has a neuroprotective effect. This study explored the pharmacological relationship between ischemia-induced cell death of the hippocampus and the efficacy of a vasodilator agent (pentoxifylline) in the...
Available crude annual incidence rates of transient ischemic attack (TIA) range between 29.0 and 61.0 cases per 100 000 in Western countries. TIA is a known predictor of subsequent ischemic stroke with risk estimates within 3 months ranging between 7.5% and 17.3%; a half of those events were described to occur within 48 hours. TIA epidemiology may have changed in recent years as a consequence o...
BACKGROUND AND THE PURPOSE OF THE STUDY Cerebral ischemia is one of the main causes of long term disability and death in aged populations. Many herbal drugs and extracts have been used for the treatment of cerebral ischemia induced insults. This study was designed to investigate the protective effect of Semelil (ANGIPARS™), a new herbal drug, on focal cerebral ischemia in male rats. MATERIAL ...
Focal brain ischemia induces inflammation, extracellular matrix remodeling, gliosis, and neovascularization. Osteopontin (OPN) is a secreted glycoprotein that has been implicated in vascular injury by promoting cell adhesion, migration, and chemotaxis. To investigate the possible involvement of OPN in brain matrix remodeling after focal stroke, we examined the expression of OPN in ischemic cort...
our aim was to report techniques and our experience in one-stage angioplasty and stenting of ostium of left common carotid and left internal carotid arteries in an octogenarian man with transient ischemic attack, who was completely recovered from neurologic insults short time after the procedure. an 81-year-old man presented with a transient ischemic attack. neurologic examination showed left s...
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