Purpose: As patients with transfusion-dependent thalassemia (TDT) are living longer, novel morbidities being recognized. The purpose of this review is to summarize the current knowledge regarding prevalence and risk factors nephrolithiasis in TDT. Methods: A non-systematic, narrative literature published up August 2021 was conducted. Results: Nephrolithiasis has been reported 18% - 59% TDT, whi...