Neonatal hyperbilirubinemia is a frequently encountered problem in the neonatal period and carries a potential risk of encephalopathy. Early detection and quantification is important, and transcutaneous bilirubinometry (TcB) has been recommended as a non-invasive method for rapid screening. We prospectively compared the efficacy of TcB in 65 normal Pakistani jaundiced newborns undergoing simult...

OBJECTIVE Preterm and low birth weight (LBW) infants are at greater risk of developing bilirubin-associated brain damage compared with term infants. Certainly, phototherapy, if used appropriately, is capable of controlling the bilirubin levels in LBW infants; but there is not a unique phototherapy treatment strategy in LBW infants. This study was designed to compare the prophylactic phototherap...

OBJECTIVE. The purpose of this work was to compare the predictive accuracy of alternative risk-assessment strategies used to screen for the risk of significant neonatal hyperbilirubinemia. PATIENTS AND METHODS.We conducted a prospective cohort study of 823 term and nearterm newborns admitted to the well-infant nursery at the Hospital of the University of Pennsylvania. Maternal, infant, and deli...

normal full-term infants were followed by serial transcutaneous bilirubinometry over the first week of life. the pattern of physiologic jaundice in our population was similar to that shown for white infants. mean maximum bilirubin peak was seen on day four of life and was also similar to that shown for american white infants. the incidence of non physiologic hyperbilirubinemia defined as 2 sd a...

A term male infant was born by spontaneous vaginal delivery to a 23 year old gravida 2 para mother. His weight, length, and head circumference were 2720g (8%), 47cm (6%) 31.5cm (1%) respectively; the remainder of his physical examination unremarkable. The pregnancy complicated intra-uterine growth retardation, gestational diabetes controlled with glyburide, thrombocytopenia. mother had past med...

BACKGROUND Jaundice in near-term and term newborns is a frequent diagnosis that may prompt hospital readmission in the first postnatal week. Hyperbilirubinemia, when excessive, can lead to potentially irreversible bilirubin-induced neurotoxicity. Predischarge risk assessment (at 24-72 hours of age) for subsequent excessive hyperbilirubinemia is feasible by a laboratory-based assay of total seru...