Due to the high interindividual response variability following transcranial direct current stimulation (tDCS), it is apparent that further research of the long-lasting effects of the stimulation technique is required. We aimed to investigate interindividual variability following anodal tDCS and cathodal tDCS in a large-scale prospective cross-over study. Motor cortex physiology measurements wer...

For several years, at the Institute Guttmann Neurorehabilitation Hospital (Barcelona, Spain), we have been applying Transcranial direct current stimulation (tDCS) for the management of Neuropathic pain after spinal cord injury. TDCS has been established as useful therapeutic option for patients with neuropathic pain [1]. Several recent studies demonstrate its efficacy, good tolerance and minima...

Background: Drug craving, the main cause of relapse and a major motivator for drug use, is a challenging obstacle in substance use treatment. Transcranial direct current stimulation (tDCS), a non-invasive neuromodulatory technique, has shown promising outcomes in treating different neuropsychiatric disorders such as drug addiction, more specifically on drug craving. The aim in the current study...

Increases in life expectancy have been followed by an upsurge of age-associated cognitive decline. Transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) have risen as promising approaches to prevent or delay such cognitive decline. However, consensus has not yet been reached about their efficacy in improving cognitive functioning in healthy older adults. Her...

Abstract High-definition transcranial direct current stimulation (HD-tDCS) seems to overcome a drawback of traditional bipolar tDCS: the wide-spread diffusion electric field. Nevertheless, most differences that characterise two techniques are based on mathematical simulations and not real, behavioural neurophysiological, data. The study aims compare widespread tDCS montage (i.e., Conventional w...

Neurologic conditions such as stroke, traumatic brain injury, tumors, and degenerative diseases are often associated with dramatic impairments in brain function. Converging evidence in the fields of clinical neurorehabilitation and cognitive neuroscience has revealed that functional recovery after brain injury depends largely on compensatory plastic changes in remaining neural structures. Thus,...

OBJECTIVE We investigate volume conduction effects in transcranial direct current stimulation (tDCS) and present a guideline for efficient and yet accurate volume conductor modeling in tDCS using our newly-developed finite element (FE) approach. APPROACH We developed a new, accurate and fast isoparametric FE approach for high-resolution geometry-adapted hexahedral meshes and tissue anisotropy...