نتایج جستجو برای: tpc

تعداد نتایج: 3260  

1999
G. R. Lynch N. J. Hadley

The PEP TPC' is a cylinder two meters long with a radius of one meter filled with argon mixed with 20% methane. The TPC can operate at pressures from one to 10 atmospheres. When a particle traverses the TPC, the electrons liberated by ionization drift parallel to the cylinder axis (z-axis) at about 5 cm per microsecond. lhe detector plane at each end is divided into six sectors, each of which h...

2005
Kirk P. Arnett Mark B. Schmidt Jung P. Shim

The authors describe integration of and multiple uses for the tablet PC (TPC) in MIS classes. These uses are geared toward enhancing student learning through the TPC rather than learning how to use a specific tool. These technologies are used in a database course and an information security course to enhance student learning by having students participate in drawing entity relationship diagrams...

Journal: :Cell stem cell 2018
Madeline N Hayes Karin McCarthy Alexander Jin Mariana L Oliveira Sowmya Iyer Sara P Garcia Sivasish Sindiri Berkley Gryder Zainab Motala G Petur Nielsen Jean-Paul Borg Matt van de Rijn David Malkin Javed Khan Myron S Ignatius David M Langenau

Tumor growth and relapse are driven by tumor propagating cells (TPCs). However, mechanisms regulating TPC fate choices, maintenance, and self-renewal are not fully understood. Here, we show that Van Gogh-like 2 (Vangl2), a core regulator of the non-canonical Wnt/planar cell polarity (Wnt/PCP) pathway, affects TPC self-renewal in rhabdomyosarcoma (RMS)-a pediatric cancer of muscle. VANGL2 is exp...

2017
Lei Lian

The incidence of ulcerative colitis (UC) is increasing in adults and children worldwide. Despite the advances in drug therapy, surgery is also an important treatment. Total proctocolectomy (TPC) with ileal pouch anal anastomosis (IPAA) is the gold standard surgical treatment of UC since its introduction in 1978 by Parks and Nicholls. Laparoscopic TPC with IPAA, as a new approach for UC patients...

2009
Wan Aida

The objective of this study was to optimise the extraction conditions for phenolic compounds from limau purut (Citrus hystrix) peels using response surface methodology (RSM). A central composite rotatable design (CCRD) was applied to determine the effects of ethanol concentration (%), extraction temperature (oC), and extraction time (min) on total phenolic content (TPC) from limau purut (Citrus...

Journal: :Molecular cancer therapeutics 2015
Nan Li Dustin J Maly Yvan H Chanthery Daniel W Sirkis Jean L Nakamura Mitchel S Berger C David James Kevan M Shokat William A Weiss Anders I Persson

Glioblastoma (GBM) is the most common malignant primary brain tumor. Radiotherapy fails to eliminate subpopulations of stem-like tumor-propagating cells (TPC), resulting in tumor regrowth. To identify kinases that promote TPC self-renewal rather than increasing proliferation in human GBM cultures, we screened a library of 54 nonselective tool compounds and determined their kinase inhibitor prof...

2017
Myron S. Ignatius Madeline N. Hayes Riadh Lobbardi Eleanor Y. Chen Karin M. McCarthy Prethish Sreenivas Zainab Motala Adam D. Durbin Aleksey Molodtsov Sophia Reeder Alexander Jin Sivasish Sindiri Brian C. Beleyea Deepak Bhere Matthew S. Alexander Khalid Shah Charles Keller Corinne M. Linardic Petur G. Nielsen David Malkin Javed Khan David M. Langenau

Tumor-propagating cells (TPCs) share self-renewal properties with normal stem cells and drive continued tumor growth. However, mechanisms regulating TPC self-renewal are largely unknown, especially in embryonal rhabdomyosarcoma (ERMS)-a common pediatric cancer of muscle. Here, we used a zebrafish transgenic model of ERMS to identify a role for intracellular NOTCH1 (ICN1) in increasing TPCs by 2...

2012
Ping Xu Jinsong Bao Junjie Gao Tao Zhou Yuefei Wang

Tea (Camellia sinensis L.) fruit peel, the main byproduct during the manufacture of tea seed oil, was used as raw material for the recovery of phenolic antioxidants. The effect of ethanol concentration, extraction time, and extraction temperature on total phenolic content (TPC) and ferric-reducing antioxidant power (FRAP) of the extracts from tea fruit peel was investigated. The maximum predict...

2007
Rachod Patachaianand Kumbesan Sandrasegaran

Power control is one of the most important mechanisms influencing on the maximum capacity and performance of Wideband Code Division Multiple Access (WCDMA) systems. Power control algorithms used in Universal Mobile Telecommunication System (UMTS) are based on fixed step size algorithms. The algorithms adjust their transmitted power based on Transmit Power Control (TPC) commands. In this paper, ...

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