INTRODUCTION Data from animal, clinical and prevention studies support the role of androgens in prostate cancer growth, proliferation and progression. Results of serum based epidemiologic studies in humans, however, have been inconclusive. The present study aims to define whether serum testosterone can be used as a predictor of a posi¬tive second biopsy in males considered for re-biopsy. MATE...

This field study investigated the release of testosterone and cortisol of a vicarious winning experience in Spanish fans watching the finals between Spain and the Netherlands in the 2010 FIFA World Cup Soccer. Spanish fans (n = 50) watched the match with friends or family in a public place or at home and also participated in a control condition. Consistent with hypotheses, results revealed that...

BACKGROUND Literature proves anti-mullerian hormone (AMH) and total testosterone (TT) as two important reproductive hormones in male development, however evidence regarding age variations of these hormones is lacking. AIMS To estimate the normal serum AMH values and to assess the age-specific TT levels in men aged 30-70, we conducted the present population-based study. METHODS A total of 83...

The purpose of this study was to determine the acute anabolic and catabolic hormone response to endurance and resistance exercise bouts of equal volume in subjects with differing training status. Twenty-two healthy men were recruited who were either resistance trained (n = 7), endurance trained (n = 8), or sedentary (n = 7). Three sessions were completed: a resting session, a 40-min run at 50-5...

BACKGROUND Children born after preeclampsia may have a dominant androgen profile in puberty compared with other children. Circulating androgen concentrations at 11-12 years of age were compared between offspring born after preeclampsia, and children whose mothers did not have preeclampsia. METHODS A total of 611 mother-offspring pairs were followed up 11 (daughters) or 12 (sons) years after b...

A correlation between serum levels of luteinizing hormone (LH), total testosterone (T), free T and sex-hormone binding globulin (SHBG) in normospermic and in oligospermic male people was done. This study was designed to measure serum levels of these hormones and of SHBG in people living at different altitude environments relative to sea level: at 209-408 meters below (the Jordan Valley, JV) and...

BACKGROUND Testosterone influences well-being, mood and cognition and may play a role in the pathophysiology of bipolar disorder. AIM To examine testosterone levels in patients with bipolar disorder compared with healthy controls. METHOD We examined baseline total testosterone levels and current depression scores in male and female patients with bipolar disorder and mild to moderate depress...

Emerging evidence links insulin resistance, a key feature in type 2 diabetes with decreased leydig cell secretion of testosterone. Low gonadal steroids, which include testosterone, dihydrotestosterone and estradiol have also been implicated with metabolic abnormalities such as hyperglycemia, hypertension and cardiovascular risk. The aim of this study was to investigate hypogonadism and its risk...

This study examined the relationship between endogenous hormones and cognitive function in nondemented, ethnically-diverse community-dwelling older men enrolled in the Einstein Aging Study (EAS). All eligible participants (185 men, mean age=81 years) received neuropsychological assessment (Free and Cued Selective Reminding Test (FCSRT), Logical Memory (LM), Trail Making Test B (TMTB), block des...

BACKGROUND The significance of testosterone as a risk factor for cardiovascular disease (CVD) in females is controversial. This cross-sectional study aimed to elucidate the relationship between serum total testosterone concentration (T-T) and augmentation index at the radial artery (r-AIx) as a marker of arterial function in Japanese postmenopausal patients. METHODS A total of 447 postmenopau...