The molar tooth sign is seen in very few conditions and is a very rare paediatric central nervous system congenital anomaly. Molar tooth sign is the result of cerebellar vermis hypoplasia, thick and maloriented superior cerebellar peduncles, and an abnormally deep interpeduncular fossa. In Joubert syndrome this is seen in about 85% of patients. We present a case of 13 months old baby boy with r...

Transposition of teeth is a severe problem, which usually affects the cuspid-first premolar area. It is frequently associated with other dental anomalies such as tooth agenesis, peg-shaped maxillary lateral incisors, retained deciduous teeth, malpositions of the adjacent teeth and other teeth malformations. This paper describes the orthodontic management with fixed appliances of a case of bilat...

OBJECTIVE To assess the prevalence of lateral incisor agenesis impacted canines and supernumerary teeth in a young adult male population. MATERIALS AND METHODS The panoramic radiographs of 1745 military students (mean age: 18.6 ± 0.52 years) who attended the Center of Aviation Medicine of the Armed Forces of Greece during the period 1997-2011 were initially analyzed for lateral incisor agenes...

The phylogenetically conserved nuclear factor I (NFI) gene family encodes site-specific transcription factors essential for the development of a number of organ systems. We showed previously that Nfia-deficient mice exhibit agenesis of the corpus callosum and other forebrain defects, whereas Nfic-deficient mice have agenesis of molar tooth roots and severe incisor defects. Here we show that Nfi...

Dental agenesis is a commonly encountered dental anomaly that affects more than 20% of the human population. It can be categorized as hypodontia, oligodontia, or anodontia. Oligodontia occur either an isolated finding part syndrome, and causative factor environmental genetic. : This report describes three cases isolated, non-syndromic tooth with single/ multiple missing permanent teeth. No othe...

Introduction: Hypodontia is one of the most prevalent craniofacial anomalies worldwide. Malocclusion could be prevented, by early treatment of this anomaly. The aim of the present study was to investigate the prevalence of congenital missing tooth (hypodontia) in patients, referred to Orthodontic Department of Kerman Dental School, as well as other private Dental Care centers. Methods: In this...

There are more than 500 anomalies caused by simple genetic factors and perhaps an equal number of others derived from multifactorial causes or chromosome aberrations where there are orofacial alterations. The frequency of symptom-less carriers of heredity anomalies that affect the teeth can be calculated from genetic data that is often essential to advise on the probability of affected offsprin...

Proper occlusion depends on the correct width ratio between upper and lower teeth, known as Bolton's ratio. In fact, this ratio can be calculated for each pair of teeth from the central incisor to the first permanent molar. This set of ratios, known as comprehensive cumulative percentage ratios (CPRs), can be used not only to determine which tooth or teeth have a tooth width discrepancy, but ca...

In spite of recent developments, data regarding the genes responsible for the less severe forms of hypodontia are still scarce and controversial. This study addressed the hypothesis that agenesis of maxillary lateral incisors (MLIA) is a distinct type of hypodontia, by evaluating its familial aggregation and the occurrence of other types of ageneses or microdontia in probands’ relatives. Sixty-...