Inactivation of Na channels has been studied in voltage-clamped, internally perfused squid giant axons during changes in the ionic composition of the intracellular solution. Peak Na currents are reduced when tetramethylammonium ions (TMA+) are substituted for Cs ions internally. The reduction reflects a rapid, voltage-dependent block of a site in the channel by TMA+. The estimated fractional el...

Both trimellitic anhydride (TMA), a small molecular weight chemical, and ovalbumin (OVA), a reference protein allergen, cause asthma with eosinophilia. To test the hypothesis that different allergens elicit symptoms of asthma via different effector pathways, gene expression was compared in lungs of Balb/c mice sensitized with either TMA or OVA, followed by intratracheal challenge with TMA conju...

This paper describes a dual-band low-profile bidirectional antenna fed by triangular monopole (TMA) with U-shaped metal cover. In addition to the higher band resonance of TMA, another lower is generated coupling between TMA and cover so that proposed has dual operation bands. The radiation patterns for both bands, peak actual gain are 2.2 dBi 4.7 at band, respectively. measured analyzed results...

Background. Atypical haemolytic uraemic syndrome (aHUS) is a rare, life-threatening disorder for which eculizumab is the only approved treatment. Life-long treatment is indicated; however, eculizumab discontinuation has been reported. Methods. Unpublished authors' cases and published cases of eculizumab discontinuation are reviewed. We also report eculizumab discontinuation data from five clini...

Abstract This work presents comprehensive numerical research on the impact load of trans-medium aircraft (TMA) using coupled Eulerian-Lagrangian (CEL) method during a water-entry event. The velocity, angle, and attitude play significant role in characteristics trajectory. In this paper, model typical TMA structure is established to study with velocity 0, 2m/s, 4m/s, 6m/s, 8m/s, angle 90°, 80°, ...

Atypical hemolytic uremic syndrome (aHUS) is a rare form of thrombotic microangiopathy (TMA) caused by uncontrolled complement activation and leading to thrombocytopenia, microangiopathic hemolysis acute kidney injury. Eculizumab, humanized monoclonal antibody that inhibits the cleavage protein C5, effectively reverses laboratory evidence TMA improves function in most patients with aHUS. Heredi...

Conversational corpus data from Mexican Spanish in Atlanta, Georgia are employed to examine tokens of second-person singular SPE (n=478) terms frequency and constraints, incorporating factors such as TMA, switch reference, specificity logistic regression analyses. Results suggest that tu, like other subjects, is strongly impacted by reference tense-mood-aspect (TMA). However, the TMA effect uni...

Cancer-related thrombotic microangiopathy (TMA) is a rare entity whose clinical and biological characteristics have been described in various tumors. Here we describe the first case of cancer-related TMA revealing diffuse bone metastases from an ethmoid sinus carcinoma.

BACKGROUND Advances of tissue microarray (TMA) technology have enabled simultaneous in situ analysis of biomarker expression in a large number of archived pathology specimens. However, the relatively high cost of TMA construction may hamper many researchers from using this essential tool of modern pathology research. We discuss methods for making TMA kits and recipient blocks for manual constru...