Background. Analyzing modern medical literature, it can be noted that in pediatric rheumatology, insufficient attention is paid to assessing the trophological status of sick children. Purpose: investigate nutritional children with various nosological forms rheumatic diseases (RD). Materials and methods. The 35 RD was investigated, which 5 patients had systemic variant juvenile idiopathic arthri...

Glutathione (GSH) and bilirubin are prominent endogenous antioxidant cytoprotectants. Despite tissue levels that are thousands of times lower than GSH, bilirubin is effective because of the biosynthetic cycle wherein it is generated from biliverdin by biliverdin reductase (BVR). When bilirubin acts as an antioxidant, it is oxidized to biliverdin, which is immediately reduced by BVR to bilirubin...

INTRODUCTION: We recently suggested that chondrocytes that are metabolically most active may make the tissue in which they reside more susceptible to undergo proteoglycan (PG)-depletion following exposure to cytokines and related factors [1]. Using chondrocytes maintained in alginate gel, we also have observed that the metabolically active cell-associated matrix (CM) is more susceptible to inte...

One of the most important problems in nutrition today is the determination of the degree of de pletion in tissue proteins associated with malnu trition and with disease. Various biochemical measurements have been developed to estimate the degree of depletion, such as the reduction of plasma albumin or of the albumin/globulin ratio, changes in the activities of certain enzyme sys tems, and alter...

P. vermicola is an opportunistic pathogen of human and animals. To estimate the pathogeneses P.vermicola in mice infected orally I/P with 1x108 CFU/ml).The histopathological changes at 24 hrs showed infiltration inflammatory cells apoptosis hepatocytes liver, around a congested blood vessel interstitial tissue kidney; lung revealed congestion vessels, alveolar emphysema; intestine appeared mono...

Declining blood CD4(+) T-cell counts mark the progress of simian immunodeficiency virus (SIV) disease in macaques and model the consequences of untreated human immunodeficiency virus infection in humans. However, blood lymphocytes are only a fraction of the recirculating lymphocyte pool, and their numbers are affected by cell synthesis, cell depletion, and distribution among blood and lymphoid ...

Sodium depletion has a protective effect on target-organ damage in hypertension independent of blood pressure. Here we tested whether chronic dietary sodium restriction may prevent the development of renal alterations associated with insulin resistance by reducing the inflammatory and oxidant state. Rats were fed normal-salt-60% fructose, low-salt-60% fructose, or control normal-salt diet for 1...

A imple model is developed to examine the performance of a supported catalytic membrane within which occurs the co-utive--parallel reaction system given by A + B + R, with rate = k, pm*’ p:, and A + R + P, with rate = kap22pF,. Closed-form sohtticms reveal that segregation of reactanti ft and B to oppmits sides of the membrane IS an effective strategy for increasing the dmired producr (R) point...

background: ionizing radiation induces the production of reactive oxygen species (ros), which play an important causative role in cell death. wholebody exposure of mice to gamma radiation leads to diminution of tissue antioxidant defense systems increases the peroxidative damage to membrane lipids and damages the haematopoietic and gastrointestinal systems. tempol (tpl), a cell membranepermeabl...