In end-stage arthritis patients, total joint replacement is a very effective surgical procedure. Nevertheless, the high revision rate after surgery remains a major concern. The wear particles generated from biomaterial-induced tissue responses may lead to chronic inflammation and local bone destruction (periprosthetic osteolysis). Several important signaling pathways are involved in wear partic...

AIM OF THE STUDY In recent years cross-linked polyethylenes have been developed in an attempt to reduce the wear, as has been demonstrated in knee simulators. The aim is to assess, by counting particles of polyethylene in synovial fluid, whether the reduction in wear is confirmed in patients with a highly crosslinked polyethylene prosthesis. MATERIAL AND METHODS A prospective randomised study...

Wear maps were developed following a series of micro-abrasion-corrosion testing during idealised hip contact conditions for a CoCrMo alloy in a foetal calf serum solution. The main aim of the study was to characterise wear-corrosion or bio-tribocorrosion regimes of the alloy over a range of applied loads and applied potentials. The transitioning micro-abrasion-corrosion mechanisms, synergisms a...

One of the major reasons for failure after total joint arthroplasty is aseptic loosening of the implant. At articulating surfaces, defined as the interface between implant and surrounding bone cement, wear particles can be generated and released into the periprosthetic tissue, resulting in inflammation and osteolysis. The aim of the present study was to evaluate the extent to which osteoblasts ...

Tribology in the railway system is of increasing interest in the new railway era due to the demand for higher speed and load capacity. Since railway vehicles operate in an open environment, their performance depends greatly on temperature, humidity and natural and artificial contaminants. Meanwhile, the “feedback” of railway vehicles to the surroundings, such as noise and airborne particles, is...

INTRODUCTION: Due to increased life expectancy at human population the amount of osteoarthritis of the knee joint will increase. The total knee replacement (TKR) is often the only way to achieve analgesia, to establish the joint function and to correct joint deformation. TKR reached a high grade of quality and safety and has become an often used surgical procedure [1]. TKR most often fail due t...

Recently, nanometre-sized UHMWPE particles generated from hip and knee replacements have been identified in vitro and in vivo. UHMWPE particles in the 0.1-1.0μm size range have been shown to be more biologically active than larger particles, provoking an inflammatory response implicated in late aseptic loosening of total joint replacements. The biological activity of nanometre-sized particles h...

INTRODUCION: Improved wear resistance of crosslinked UHMWPE has been well demonstrated in both hip and knee [1-4]. A reduction of 70% can be shown in knee simulators from conventional crosslinked tibial inserts (CXPE) gamma-irradiated at 3.5Mrad to 7Mrad highly crosslinked inserts (HXPE). Hip simulator models indicated that debris size decreased with increased crosslinking [5]. In the knee it h...

Oil debris sensors are effective tools to monitor wear particles in lubricants. For in situ applications, surrounding noise and vibration interferences often distort the oil debris signature of the sensor. Hence extracting oil debris signatures from sensor signals is a challenging task for wear particle monitoring. In this paper we employ the maximal overlap discrete wavelet transform (MODWT) w...