Chronic subjective tinnitus is characterized by abnormal neuronal synchronization in the central auditory system. As shown in a controlled clinical trial, acoustic coordinated reset (CR) neuromodulation causes a significant relief of tinnitus symptoms along with a significant decrease of pathological oscillatory activity in a network comprising auditory and non-auditory brain areas, which is of...

In this preliminary report, we present the results from our investigation of 34 tinnitus patients for tinnitus suppression with frequency-specific sound stimuli within the auditory spectrum. Of this number, 22 (64.7%) experienced suppression, 5 (14.7%) had partial suppression, and 7 (20.6%) were nonresponders. Suppression of peripheral tinnitus may result when mechanosensitive outer hair cells ...

A new device and method described here will allow real-time processing of any audio signal (e.g., from a television set) into a high-frequency tinnitus sound therapy stimulus. By simultaneously listening to the unprocessed and processed speech, a patient can enjoy the entertainment while obtaining therapy that appears to be a viable alternative in the treatment of severe disabling tinnitus.

We summarize our long-term clinical experiences with an inner-ear drug delivery system (DDS) for control of tinnitus. The inner-ear DDS consist of transtympanic perfusion of 2 or 4 mg dexamethasone to the round window via the middle ear. Therapeutic results of steroid targeting therapy to the inner ear were evaluated in 3,978 ears of 3,041 patients. Tinnitus improved in 75% of these patients im...

Background The perception of sound in the absence of an external sound is tinnitus. Tinnitus can have a severe negative impact on quality of life. Objective This trial investigated whether multisession anodal transcranial direct current stimulation (tDCS) of the left temporoparietal area would enhance sound therapy from hearing aids. Methods Forty participants (mean age = 54 years) experiencing...

Objectives: A randomized cross-over trial in 18 participants tested the hypothesis that nature sounds, with unpredictable temporal characteristics and high valence would yield greater improvement in tinnitus than constant, emotionally neutral broadband noise. Study Design: The primary outcome measure was the Tinnitus Functional Index (TFI). Secondary measures were: loudness and annoyance rating...

Connectionist modeling is applied to issues in cognitive rehabilitation, concerning the degree and speed of recovery through retraining, the extent of generalization to untreated items, and how treated items are selected to maximize this generalization. A network previously used to model impairments in mapping orthography to semantics is retrained after damage. The degree of relearning and gene...

Tinnitus is the perception of sound occurring without an external stimulus. Sound therapy is one of the most effective treatment techniques that have been employed by clinicians. To account for mechanisms of tinnitus generation and the clinical effects of sound therapy from the viewpoint of neural engineering, the authors have proposed a conceptual neural oscillator model with plasticity for th...

Objectives: Acoustic stimulation or sound therapy is proposed as a main treatment option for chronic subjective tinnitus. To further probe the field of acoustic stimulations for tinnitus therapy, this exploratory study compared 10 Hz amplitude modulated (AM) sounds (two pure tones, noise, music, and frequency modulated (FM) sounds) and unmodulated sounds (pure tone, noise) regarding their tempo...

BACKGROUND: This study was undertaken to assess long-term changes in tinnitus severity exhibited by patients who completed a comprehensive tinnitus management program; to identify factors that contributed to changes in tinnitus severity within this population; to contribute to the development and refinement of effective assessment and management procedures for tinnitus. METHODS: Detailed questi...