The advent of social media have allowed us to build massive networks of weak ties: acquaintances and nonintimate ties we use all the time to spread information and thoughts. Conversely, strong ties are the people we really trust, people whose social circles tightly overlap with our own and, often, they are also the people most like us. Unfortunately, the social media do not incorporate tie stre...

The advent of social media have allowed us to build massive networks of weak ties: acquaintances and nonintimate ties we use all the time to spread information and thoughts. Conversely, strong ties are the people we really trust, people whose social circles tightly overlap with our own and, often, they are also the people most like us. Unfortunately, the majority of social media do not incorpor...

TIE is a receptor tyrosine kinase expressed in both mature endothelial cells and their precursors, as well as in some hematopoietic cells. Mouse embryos homozygous for a disrupted Tie allele die at midgestation due to impaired endothelial cell integrity and resulting hemorrhage. Here we have performed chimeric analysis to study further the function of the murine TIE in the development of embryo...

This paper explores the impact of communication media and the Internet on connectivity between people. Results from a series of social network studies of media use are used as background for exploration of these impacts. These studies explored the use of all available media among members of an academic research group and among distance learners. Asking about media use as well as about the stren...

Social capital and social support are two key constructs in the study of social networks and health. Despite their importance, little research has sought to examine the characteristics of those social ties by which individuals access social capital and support resources. Network diversity - a key structural feature in accessing social capital - refers to a person's broad but generally weak and ...

Relational diversity can be characterized by heterogeneous distributions of tie strengths in social networks and this diversity is present not only among humans, but throughout the animal world. We account for this observation by analyzing two network datasets from Facebook. We measure the strength of a tie by calculating the extent of overlap of friends between the two individuals. Based on th...

A receptor tyrosine kinase (RTK), TIE (tyrosine kinase that contains immunoglobulin-like loops and epidermal growth factor [EGF] homology domains), is expressed in vascular endothelial and hematopoietic cells. We generated monoclonal antibodies (MoAbs) against the extracellular domain of TIE and a polyclonal antibody against the TIE carboxyterminus and used them to analyze expression of TIE in ...

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