Thyrotoxicosis is the clinical syndrome of hypermetabolism that occurs with increased levels of thyroid hormones. Thyroid storm (TS) represents the extreme manifestation of thyrotoxicosis. Medical charts of all pediatric patients with the diagnosis of “Thyroid Storm or “Impending Thyroid Storm” (ITS) from 2004 to 2010 were retrieved. Patients with a BWC of 25 and above were included. Charts wit...

Hepatic dysfunction in a patient with thyrotoxicosis may result from hyperthyroidism per se, as a side effect of antithyroid drugs, and causes unrelated to hyperthyroidism which sometimes causes diagnostic and therapeutic difficulties. A young female patient was admitted to our hospital with symptoms of thyrotoxicosis, diffuse goiter and ophthalmopathy along with cholestatic pattern of jaundice...

Background: It is well known that thyrotoxicosis causes rhythm disorders including sinus tachycardia, atrial fibrillation, and atrial flutter. Atrial fibrillation is the most common arrhythmia in thyrotoxicosis, occurring in 5–15% of patients over 60 years of age, whereas ventricular arrhythmia is an unusual manifestation. Case Report: An 18-year-old Japanese woman was admitted to our emergency...

Gestational transient thyrotoxicosis refers to non-autoimmune hyperthyroidism in pregnant women and it is associated with hyperemesis gravidarum. During pregnancy, there are some alterations in thyroid gland, such as elevation of thyroxine binding globulin, increased iodium clearance in kidneys, and stimulation of thyroid gland by human chorionic gonadotropin. Hitherto, the pathophysiology unde...

Although pituitary function is often impaired in pituitary apoplexy, the development of thyrotoxicosis is rare. We describe an unusual case of hypopituitarism due to pituitary apoplexy coexisting with transient hyperthyroidism. A 74-year-old woman presented with severe fatigue, palpitation, appetite loss, hypotension, and hyponatremia. Endocrine studies showed hyperthyroidism and anterior pitui...

PURPOSE Graves disease is the most common cause of hyperthyroidism in children. Inorganic iodide has been used in combination with antithyroid drugs for more effective normalization of thyroid hormones in some cases of severe thyrotoxicosis. This study aimed to investigate clinical characteristics of childhood thyrotoxicosis and effectiveness of inorganic iodide in the early phase of treatment....

TACHYCARDIA is a characteristic feature of thyrotoxicosis at all ages, but the older the patient the more frequent the occurrence of atrial fibrillation. Treatment of thyrotoxicosis is followed by slowing of heart rate and more than half of the thyrotoxic patients with atrial fibrillation, who are treated with anti-thyroid drugs or surgery (Sandler & Wilson, 1959) or radioactive iodine therapy ...

INTRODUCTION Hyperthyroidism is characterized by increased synthesis and release of thyroid hormones by the thyroid gland. Thyrotoxicosis refers to the clinical syndrome resulting from excessive circulating thyroid hormones, secondary to hyperthyroidism or due to other causes. This article describes evidence-based guidelines for the clinical management of thyrotoxicosis. OBJECTIVE This consen...

Interferon-alpha (IFN ) is a therapeutic agent which is used for infectious and malignant diseases. Side effects such as flu-like symptoms, hematologic abnormalities and thyroid disease have been reported associated with this therapy. Thyroid disease manifests as development of thyrotoxicosis and it may be secondary to destructive thyroiditis or Graves’ disease. Here we report a 61-year-old fem...