INTRODUCTION There are many adverse effects that have been described for isotretinoin. To the best of our knowledge, this is the first report of a possible association of oral isotretinoin intake with autoimmune thyroiditis and ocular myasthenia gravis (OMG). CASE PRESENTATION A 19-year-old Caucasian male, who had used oral isotretinoin for severe acne disease for the previous six months, was...

BACKGROUND Several epidemiological studies on the prevalence of hypothyroidism in the elderly have been reported; however, extensive series of elderly patients with thyroid dysfunction have not been studied. Our aim has been to assess the relative frequency of the diverse causes of hypothyroidism in a group of patients older than 55 years and the adequacy of control of thyroid function attained...

hashimoto’s thyroiditis, the most common autoimmune thyroid disease, is due to destruction of the thyroid gland by autoantibodies. various types of thyroid malignancies may arise in hashimoto’s thyroiditis. follicular carcinomas, papillary carcinomas, lymphomas, medullary carcinomas and hurthle cell neoplasms may develop in hashimoto’s thyroiditis. we present a rare case report of a 35-year-old...

Multiple sclerosis (MS) is an autoimmune, inflammatory disease characterized by demyelination and axonal degeneration in the central nervous system. MS is the second major cause of disability following trauma, and is mostly seen between the ages of 20 - 40 years and in women. Autoimmune hepatitis (AH) is a chronic disease characterized by hypergammaglobulinemia, high levels of transaminases, pr...

We report a case of severe hypothyroidism with nongoitrous, autoimmune thyroiditis and pituitary hyperplasia in a 13-year-old boy, who presented with sudden palsy on the left side of his face. Prednisolone and antiviral medication was administered. However, the facial palsy did not improve completely. The medications were replaced with thyroxine, and the facial palsy recovered. Endocrinological...

Interferon alpha (IFN-alpha) therapy is associated with a number of immunological side-effects, including autoimmune diseases and a 10% prevalence of thyroiditis. Hepatitis C virus (HCV) infection itself predisposes to autoimmune phenomena including hypothyroidism and myositis. The development of clinical hypothyroidism in the presence of positive thyroid antibodies in patients infected with HC...

351 Prevalence of Thyroid Peroxidase Autoantibodies (ANTI-TPO) in Women with Autoimmune Connective Tissue Diseases (ACTD) Georgios Papadopoulos, MD, Anastasia Vakaloudi, PhD, Eirene Koutsika, MD, Ekarerini Anastasiou, MD, and Asimoula Koteli, MD. Immunology Laboratory, General Hospital Agios Pavlos, Thessaloniki, Greece. Background: Chronic autoimmune thyroiditis, manifested by positive test fo...

351 Prevalence of Thyroid Peroxidase Autoantibodies (ANTI-TPO) in Women with Autoimmune Connective Tissue Diseases (ACTD) Georgios Papadopoulos, MD, Anastasia Vakaloudi, PhD, Eirene Koutsika, MD, Ekarerini Anastasiou, MD, and Asimoula Koteli, MD. Immunology Laboratory, General Hospital Agios Pavlos, Thessaloniki, Greece. Background: Chronic autoimmune thyroiditis, manifested by positive test fo...

351 Prevalence of Thyroid Peroxidase Autoantibodies (ANTI-TPO) in Women with Autoimmune Connective Tissue Diseases (ACTD) Georgios Papadopoulos, MD, Anastasia Vakaloudi, PhD, Eirene Koutsika, MD, Ekarerini Anastasiou, MD, and Asimoula Koteli, MD. Immunology Laboratory, General Hospital Agios Pavlos, Thessaloniki, Greece. Background: Chronic autoimmune thyroiditis, manifested by positive test fo...

This review focuses on two different topics: (a) iodine and autoimmune thyroid disease (AITD) and (b) AITD and papillary thyroid carcinoma (PTC). Iodine intake modifies the expression of thyroid diseases and has been associated with induction of AITD. Thyroglobulin (Tg) is an important target in iodine-induced autoimmune response due to post-translational modifications of iodinated Tg, as sugge...