Sir The risk of developing thyroid dysfunction is higher in Turner syndrome (TS) than the general population 1,2 . In previous studies, the influence of karyotype 3 and thyroid autoantibodies 4 on thyroid disorder in patients with TS has been investigated. We therefore set out to determine the prevalence of thyroid dysfunction in Irish girls with TS. The impact of underlying karyotype and thyro...

The trace element selenium (Se) occurs in the form of the amino acid selenocysteine in selenoproteins. Selenoproteins exerts multiple physiological effects in human health, many of which are related with regulation of reduction-oxidation processes. In fact, the selenoenzyme families of glutathione peroxidase (GPx) and thioredoxin reductase (TRx) display the ability to act as antioxidants, prote...

The aim of the study was to evaluate the natural course and potential risk factors of autoimmune thyroiditis (AIT) and thyroid dysfunction, and their influences on growth and glycemic control in children and adolescents with type 1 diabetes mellitus (T1D). The study comprised 148 subjects (age range 1-21 years; males 51%) with T1D. During the interval of 12 years serum levels of thyroid peroxid...

Breast cancer is a hormone-dependent neoplasm. Conflicting results regarding the clinical correlation between breast cancer and thyroid diseases have been reported. The aim of this study was to determine the goiter prevalence, thyroid hormones and antithyroid antibody levels in patients with breast cancer. For this purpose, thyroid ultrasonography was performed and serum levels of free triiodot...

BACKGROUND The end-diastolic velocity (EDV) of thyroid arteries reflects peripheral blood flow resistance. OBJECTIVE The aim was to evaluate EDV correlations with other Doppler sonography parameters and with clinical and biochemical variables in a sample of patients with hypothyroidism caused by chronic autoimmune thyroiditis (CAT). METHODS A sample of 48 CAT hypothyroid patients receiving ...

BACKGROUND Thyroid peroxidase (TPO) is essential for physiological function of the thyroid gland. The high prevalence of thyroid peroxidase antibodies (TPOAbs) in patients with breast cancer and their protective role had previously been demonstrated, indicating a link between breast cancer and thyroid autoimmunity. Recently, TPO was shown to be present in breast cancer tissue samples but its an...

Fetal goiter is an uncommon, serious problem during pregnancy. Careful routine antenatal ultrasound screening can find out an intrauterine fetal goiter. Fetal goiter has an incidence of 1:40000 live births (1). 80% of cases are caused by dysgenesis of the thyroid gland. The rest 5% and 15% are due to hypothalamohypophyseal abnormalities and dyshormonogenesis, respectively. 8% of cases are due t...

Autoimmune diseases of the thyroid gland (ADTG) which include, Graves' disease, Hashimoto thyroiditis, primary hypothyroidism with atrophic thyroiditis, postpartum thyroiditis and 'silent' thyroiditis, are characterized by the presence of serum thyroid autoantibodies (TAB). Thyroid autoantibodies are not rare even in the general population of all ages, and their presence in women is 5 times mor...

Background: Thyroid disorders are the most second endocrine problem after diabetes mellitus in society. Environmental, immunological, and genetic factors lead to development of thyroid disorders. Objectives: The study intended evaluate role antibodies hormones diagnosis diseases, as well prevalence patients having living Shendi locality. Study design: current research was prospective, case - co...